نتایج جستجو برای: gene prediction

تعداد نتایج: 1377029  

Journal: :Journal of the American Medical Informatics Association : JAMIA 2012
David K. Crockett Elaine Lyon Marc S. Williams Scott P. Narus Julio C. Facelli Joyce A. Mitchell

The rapid advance of gene sequencing technologies has produced an unprecedented rate of discovery of genome variation in humans. A growing number of authoritative clinical repositories archive gene variants and disease phenotypes, yet there are currently many more gene variants that lack clear annotation or disease association. To date, there has been very limited coverage of gene-specific pred...

بانه, حسن, رحیمی میانجی, قدرت, نجاتی جوارمی, اردشیر, هنرور, محمود,

The current study was carried out to evaluate accuracy of some Bayesian methods for genomic breeding values prediction for threshold traits with different types of genetic architecture based on distribution of gene effect and QTL numbers. A genome consisted of 3 chromosomes of 100 CM with 2000 single nucleotide polymorphisms (SNP) was simulated. The QTL numbers were 0.01, 0.05 and 0.1 of total ...

Journal: :Journal of computational biology : a journal of computational molecular cell biology 2002
Michael D. Radmacher Lisa M. McShane Richard M. Simon

We propose a general framework for prediction of predefined tumor classes using gene expression profiles from microarray experiments. The framework consists of 1) evaluating the appropriateness of class prediction for the given data set, 2) selecting the prediction method, 3) performing cross-validated class prediction, and 4) assessing the significance of prediction results by permutation test...

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