Atypical manifestation of Huntington's disease (HD) could inform ongoing research into HD genetic modifiers not present in the primarily European populations studied to date. This work demonstrates that expanding HD genetic testing into under-resourced healthcare settings can benefit both local communities and ongoing research into HD etiology and new therapies.

Genealogical or coalescent methods have proved very useful in interpreting and understanding a wide range of population genetic data. Our aim is to illustrate some of the central ideas behind this approach. The primary focus is genealogy in neutral genetic models, for which the effects of demography can be separated from those of mutation. We describe the coalescent for panmictic populations of...

AUTOMATING THE EXTRACTION OF DOMAIN SPECIFIC INFORMATION FROM THE WEB—A CASE STUDY FOR THE GENEALOGICAL DOMAIN Troy Walker Department of Computer Science Master of Science Current ways of finding genealogical information within the millions of pages on the Web are inadequate. In an effort to help genealogical researchers find desired information more quickly, we have developed GeneTIQS, a Genea...

In this paper, we formulate six different resolutions of a continuous-time approximation of the Wright-Fisher sample genealogical process. We derive Markov chains for the six different approximations in the spirit of J.F.C. Kingman. These Markov chains are essential for inference methods. One of the resolutions is the well-known n-coalescent due to Kingman. The second resolution was mentioned b...

Genetic divergence in the form of the mandible is examined in ten inbred strains of mice. Several univariate and multivariate genetic distance estimates are given for the morphological data and these estimates are compared to measures of genealogical and molecular divergence. Highly significant divergence occurs among the ten strains in all 11 mandible traits considered individually and simulta...

The idea of ‘plague’ has returned to public consciousness with the arrival COVID-19. An anachronistic and extremely problematic concept for thinking about biopolitical catastrophe, plague nevertheless offers an enormous historical range a potentially highly generative metaphorical framework psychosocial studies engage with, example, through Albert Camus’ (2013) Plague Sophocles’ (2015) Oedipus ...

On-line genealogy is becoming America’s latest craze [1]. The LDS church’s FamilySearch website contains only a fraction of the information that is available on the Web. People around the world, both members and non-members, have posted family trees and other genealogical information on tens of thousands of websites throughout the Web. Although the genealogical data posted by individuals repres...

The most slow and tedious job in genealogical research is searching civil or church records for information about an individual. But, this is an essential step in research. By searching multiple sources such as census records, wills, deeds, birth and death records we can compile a more complete set of information, and potentially the pedigree of an individual. When records are stored electronic...

The article examines the organizational patterns of nineteenth-century Swiss Alpine geology. It argues that early and middle nineteenth-century Swiss geognosy was shaped in genealogical terms and that the patterns of genealogical reasoning and practice worked as a vehicle of transmission toward the generalization of locally gained empirical knowledge. The case study is provided by the Zurich ge...

15.4.2011 The genealogical ancestors to an individual are the the individuals that can be reached by a string of operators mother/father to that individual, like motherfatherfather. Within that set are the individuals, that has genetic material that was transmitted to the present individual. Genetic ancestry is in general given more attention as that is a component in genetic analysis and mapp...