The eleven essays cover the following subjects: Inflammation and Tissue Injury, by Ward; Cellular Basis of Immunoglobulin Synthesis, by Mullinax; Immunoglobin Structure and Biological Implications, by Bennett; Molecular Aspects of Antigen-Antibody Binding as Related to the Initiation of Immunological Reactions, by Siskind and Levine; Complement Components, by Stroud; Complement and Its Role in ...

TO THE EDITOR—We read with interest the updated guidelines for the management of skin and soft tissue infections from the Infectious Diseases Society of America [1]. Their effort to expand on drug dosing is clear and appreciated. However, we would like to draw attention to a few dosing discrepancies. Table 3 [1] lists regimens for the treatment of intestinal or genitourinary tract infections fo...

The receptor tyrosine kinase ret protooncogene (RET) is implicated in the pathogenesis of several diseases and in several developmental defects, particularly those in neural crest-derived structures and the genitourinary system. In order to further elucidate RET-mediated mechanisms that contribute to these diseases and decipher the basis for specificity in the pleiotropic effects of RET, we cha...

Humans are the only natural reservoir for meningococci. The appropriate specimens that should be taken for isolation of meningococci are dependent on the clinical question. The most appropriate specimen and/or laboratory techniques for microbiological diagnosis in an acutely sick patient with suspected invasive disease like meningitis/septicemia (1) may be quite different from those required fo...

PURPOSE Congenital and acquired pathologies of the seminal vesicles (SV) are rare diseases. The diagnosis of SV anomalies is frequently delayed or wrong due to the rarity of these diseases and the lack of adequate evaluation of SV pathology. For this reason, we aimed to comprehensively evaluate SV pathologies and accompanying genitourinary system abnormalities. MATERIALS AND METHODS Between M...

Amyloidosis is a pathological process characterized by extracellular deposition of proteinaceous substance. This is an endpoint for a variety of disease processes and can be generalised or localised. Amyloidosis of the lower urinary tract is unusual and has varied presentation. It is noted more commonly than expected and may be seen in patients with a background of chronic inflammatory disorder...

Abstract The aim of imaging in children with congenital and acquired abnormalities the genitourinary system is to increase quality care by establishing an accurate diagnosis guiding child’s management. Pediatric urological conditions are diverse many different approaches We will present a concise overview most important common disorders pediatric urogenital tract.

Congenital or neonatal rhabdomyosarcoma is a rare entity, usually presenting as masses in the head and neck region as well as genitourinary tract. The embryonal variant is the most common type occurring in infancy. This is a case of congenital rhabdomyosarcoma with a huge forearm mass, with metastatic discrete nodules in the soft tissues of the neck and scapular region, resembling a ‘blueberry ...