This study evaluated daily cleaning with germicidal bleach wipes on wards with a high incidence of hospital-acquired Clostridium difficile infection (CDI). The intervention reduced hospital-acquired CDI incidence by 85%, from 24.2 to 3.6 cases per 10,000 patient-days, and prolonged the median time between hospital-acquired CDI cases from 8 to 80 days.

Several approaches for the inactivation of bacteriophage lambda, including UV germicidal irradiation (UVGI) and the chemical agents Virkon-S, Chloros, Decon-90, and sodium hydroxide (NaOH), were compared. Virkon, NaOH, and UVGI caused a ≥7-log(10) reduction in phage titers. This study successfully describes several methods with potential for bacteriophage inactivation in industrial settings.

agent technology is an emerging and promising research area in software technology, which increasingly contributes to the development of value-added information systems for large healthcare organizations due to its capability to automatically modify themselves in response to changes in their operating environment. multi agent system (mas) approach is the construction of a complex system as a se...

As part of a project to validate a UV reactor for disinfection of drinking water, the germicidal output of four medium pressure lamps housed in a continuously operating reactor was followed as a function of time. Spectra were measured monthly and were used in conjunction with radiometer readings to calculate germicidal fluence rates (using DNA absorbance weighting) at the radiometer sensor posi...

IN order to make a jucdicious clhoice of the antiseptic most likely to give useful results in the treatment of infected wounds m:lany different factors lhave to be considered in addition to germicidal activity, including tlle irritating properties of the substances, their toxicity, solubility, ability to penetrate tissues and to be absorbed, and their chemical reactions with proteins and other ...

Langheld (1) found that sodium hypochlorite reacts with a-amino acids to form chloramino acids, which more or less readily break down to aldehydes or ketones, ammonia, carbonic acid, and sodium chloride. Milroy (2) pointed out that in the case of aromatic or heterocyclic amino acids, such as tyrosine or tryptophane, partial chlorination of the ring takes place in addition to oxidation. Hypochlo...