Gingival overgrowths found in the oral cavity are mostly due to reactive hyperplasia and rarely depict neoplastic nature. It is a challenge for the clinician to give final diagnoses of gingival overgrowth. Gingiva is a common site for various benign and malignant lesions. Oral cavity is an ideal niche for the manifestation of various precancerous and cancerous lesions. Fibrous growths present i...

Many systemic illnesses manifest clinical signs in the oral cavity. A remarkable case of gingival hyperplasia heralding the presence of acute myelomonocytic leukemia (AML FAB-M4) is described. The oral manifestations of acute leukemia are reviewed.

OBJECTIVES 4-nitroquinoline 1-oxide (4NQO)-induced rat tongue carcinogenesis is a useful model for studying oral squamous cell carcinoma. However, gingival changes following 4NQO administration via drinking water are absent in the literature. The aim of this study was to investigate gingival changes concomitant to tongue carcinogenesis induced by 4NQO by means of morphological analysis. METHO...

The pathogenesis of gingival overgrowth is uncertain and the treatment is still largely limited to the maintenance of an improved level of oral hygiene and surgical removal of the overgrown tissue. This case report describes the interdisciplinary approach to restore function and esthetics of an edentulous area with gingival overgrowth in the premaxilla region. The periodontal treatment plan inc...

Phenytoin (diphenlhydantion or Dilantin) is a highly effective and widely prescribed anticonvulsant agent and antiarrhythmic agent in the treatment of grand mal and psychomotor epilepsy. Phentoin was introduced into therapy in 1937 for effective convulsive disorder with a common side effect being gingival hyperplasia. In dermatology due to the stimulatory effect on the connective tissue it is u...

INTRODUCTION Many factors can contribute to the development of gingival overgrowth (hyperplasia), including: plaque control; periodontal variables; medications and their relative dose; age; sex; and, genetic factors. Nifedipine is a calcium channel blocker commonly reported to result in drug-induced gingival overgrowth (DIGO). This report outlines a case of gingival overgrowth induced by amlodi...

Orthodontic treatment with fixed appliances that is mediated by the power forces of apparatus might lead to changes in blood circulation, predispose a number complications such as tooth movement and contributes morphological bone tissue remodeling. We have investigated 126 patients aged 16–35 years after appliance bracket therapy has caused orthodontically induced gingival hyperplasia. Immunolo...