نتایج جستجو برای: glanzmanns thrombasthenia
تعداد نتایج: 525 فیلتر نتایج به سال:
background: the present study evaluated treatment outcomes and the treatment indexes among glanzmann’s patients in mofid children’s hospital, tehran, iran. patients and methods: a retrospective cross-sectional study was performed to evaluate the treatment protocols on 15 glanzmann’s patients with bleeding therapeutic records in mofid children’s hospital, tehran, iran, from 2006 to 2011. results...
Glanzmann thrombasthenia is an autosomal recessive bleeding disorder characterized by a life-long hemorrhagic tendency and absent or severely reduced platelet aggregation in response to agonists. The thrombasthenic phenotype is associated with quantitative or qualitative abnormalities in the platelet fibrinogen receptor, the αIIbβ3 integrin or glycoprotein (GP) IIb-IIIa, which can also serve as...
PLASMA CLOTTING FACTOR is deficient in most of the “experiments of nature” that have helped to further our understanding of the mechanism of blood coagulation and hemostasis, but in thrombasthenia the defect lies in the platelets which are unable to promote clot retraction. Thrombasthenic patients usually have a mild to moderately severe hemorrhagic diathesis, with a prolonged bleeding time. Th...
Patients with inherited bleeding disorders are rare in obstetric practice but present with prolonged bleeding even after minor invasive procedures. They require a combined approach with obstetric and hematological management of each case, including the neonatal management of a possibly affected fetus. We present the case of a pregnancy in a patient with combined Factor VII deficiency and Glanzm...
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