The implant described in this communication is the direct descendent of a long series of artificial drainage devices which began when Zorab (I9I2) inserted a silk thread through the limbus in order to drain aqueous into the subconjunctival space in cases of glaucoma (see also Mayou, I9I2). Among the more recently described devices are teflon drainage tubes in man (Richards, I955; Epstein, 1959;...

OBJECTIVE We sought to compare the efficacy, safety, and cost of intraoral drainage (IOD) of parapharyngeal abscesses (PPAs) in the pediatric population with those of the more commonly used external neck drainage (END). PATIENTS AND STUDY DESIGN AND SETTING: An 11-year retrospective review was conducted of all patients admitted to a tertiary-care, university-affiliated, pediatric hospital with ...

PURPOSE Ab interno trabeculectomy (AIT) with the Trabectome has been shown to reduce intraocular pressure (IOP) in eyes with pseudoexfoliation (PEX) glaucoma. Here, we examined the change of IOP fluctuations before and after only AIT or AIT with cataract surgery in PEX patients using the contact lens sensor Triggerfish®. METHODS This was a prospective open-label study. Twenty-four consecutive...

Purpose Glaucoma-related molecular biomarkers can improve clinical testing to diagnose the disease early, predict its prognosis, and monitor treatment responses. Based on the evidence of increased oxidative stress in glaucomatous tissues, this study analyzed oxidative stress-related biomarker candidates in blood and aqueous humor samples with or without glaucoma. Methods The blood and aqueous...

High Intraocular Pressure (IOP) for longer period of time may guide the eye to different deceases and Glaucoma is one of them. Continuous, non-invasive and comfortable way of measuring IOP is necessary to detect the high IOP at the very early stage. Few methods are involved widely to measure the IOP in the doctor’s chamber. Some other methods can be used by the person himself but those are stil...

OBJECTIVE To evaluate the efficacy and tolerability of Ex-PRESS implantation (Ex-Press) compared with trabeculectomy (Trab) in the treatment of patients with uncontrolled glaucoma. METHODS A comprehensive literature meta-analysis was performed according to the Cochrane Collaboration methodology to identify controlled clinical trials comparing Ex-Press with Trab. Efficacy estimates were measur...

OBJECTIVE To create and test a slow-release antifibrotic drug-coated glaucoma drainage device using in vitro and in vivo experiments. METHODS A slow-release device incorporating mitomycin C in poly(2-hydroxyethyl methacrylate) disks was developed using redox-polymerization techniques. A standardized preparation of this drug delivery device was attached to the Ahmed glaucoma valve (model FP7; ...