نتایج جستجو برای: gliadin antibody

تعداد نتایج: 167489  

Journal: :Journal of Immunology 2023

Abstract Wheat is one of the major allergenic foods capable eliciting life-threatening anaphylaxis. Discovering potential hypo/hyper-allergenic wheat classes imperative to advance our knowledge and manage allergy. Durum (genome AABB) soft white AABBDD) are two commonly consumed wheats. However, whether there differences in intrinsic allergenicity between them unknown. Here, we tested hypothesis...

Journal: :Nutritional neuroscience 2004
A Vojdani T O'Bryan J A Green J Mccandless K N Woeller E Vojdani A A Nourian E L Cooper

The mechanisms behind autoimmune reaction to nervous system antigens in autism are not understood. We assessed the reactivity of sera from 50 autism patients and 50 healthy controls to specific peptides from gliadin and the cerebellum. A significant percentage of autism patients showed elevations in antibodies against gliadin and cerebellar peptides simultaneously. For examining cross-reaction ...

Journal: :Neurology 2003
Anne H Cross Paul T Golumbek

Celiac disease (celiac sprue or gluten-sensitive enteropathy) is an inflammatory autoimmune disease of the small intestine that occurs in genetically susceptible (HLA DQ2 or DQ8 ) individuals upon exposure to dietary gluten.1 Gluten (gliadin and glutenin, found in wheat, rye, and barley) comprises a family of prolineand glutamine-rich proteins. Celiac disease is common, affecting 0.5 to 1% of t...

امیری, رضا , دخانی, شهرام , رضایی, عبدالمجید , شاهدی, محمد,

This study was conducted to evaluate the capability of reversed-phase high performance liquid chromatography (RP-HPLC) of wheat (Triticum aestivum L.) storage proteins, and their genetic variability in different winter and spring isolines, cultivars and landraces. Gliadin proteins were extracted from the flour of five randomly selected seeds of each genotype. In this method, Nucleosil C18 300 A...

2013
Merlin Nanayakkara Giuliana Lania Mariantonia Maglio Roberta Kosova Marco Sarno Alessandra Gaito Valentina Discepolo Riccardo Troncone Salvatore Auricchio Renata Auricchio Maria Vittoria Barone

Celiac disease (CD) occurs frequently, and is caused by ingestion of prolamins from cereals in subjects with a genetic predisposition. The small intestinal damage depends on an intestinal stress/innate immune response to certain gliadin peptides (e.g., A-gliadin P31-43) in association with an adaptive immune response to other gliadin peptides (e.g., A-gliadin P57-68). Gliadin and peptide P31-43...

Journal: :Biopolymers 2009
Li Liang Maud Pinier Jean-Christophe Leroux Muriel Subirade

The wheat gluten protein alpha-gliadin, a well known trigger of celiac disease, can be complexed by random copolymers of hydroxyethyl methacrylate (HEMA) and sodium 4-styrene sulfonate (SS). In this work, influence of alpha-gliadin and poly(HEMA-co-SS) concentrations on alpha-gliadin structure was studied using spectroscopic techniques and dynamic light scattering. In 70% ethanol or 0.06M HCl (...

Journal: :Journal of immunology 2007
Giuseppe Terrazzano Michela Sica Carmen Gianfrani Giuseppe Mazzarella Francesco Maurano Beatrice De Giulio Sophie de Saint-Mezard Delia Zanzi Luigi Maiuri Marco Londei Bana Jabri Riccardo Troncone Salvatore Auricchio Serafino Zappacosta Ennio Carbone

We analyzed the autologous NK cell interaction with gliadin-presenting dendritic cells. Gliadin is the known Ag priming the celiac disease (CD) pathogenesis. We demonstrate that gliadin prevents immature dendritic cells (iDCs) elimination by NK cells. Furthermore, cooperation between human NK cells-iDCs and T cells increases IFN-gamma production of anti-gliadin immune response. Gliadin fraction...

2013
Narendra Reddy Yiqi Yang

For the first time, gliadin films with excellent strength and water stability have been developed without using any crosslinking agents. So far, it has not been possible to obtain water stable gliadin films even after crosslinking. In this research, a novel method of using aqueous urea and ethanol has been developed to obtain highly water stable gliadin films without using crosslinking chemical...

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