After 6 weeks of treatment with 17;6-estradiol, two distinct groups of female NZB/ NZW mice were identified. Group I females developed significant increases in serum f f 2 , pand y-globulins and had few serologic abnormalities. Serum globulins did not increase in Group I1 females. This blunted response correlated with a pretreatment increase in the frequency of positive tests for ANA, LE phenom...

Two major proteins (the 7S and 11S globulins) of soybean (Glycine max) were simultaneously isolated by a simple method based on their different solubilities in dilute tris (hydroxymethyl) aminomethane buffers. The purified 7S globulins, which represented essentially the entire 7S soybean protein fraction capable of dimerization at 0.1 ionic strength, were fractionated into five components by di...

UTOMATIC ESTIMATION of serum globulins in human serum is normally measured as the difference between the total protein and the albumin as estimated by the dye binding capacity of the albumin, usually using 2-(4’hydroxyazobenzene) (HABA). However, it has been shown that a variety of drugs will upset dye uptake by the albumin (1). In addition, the absorbance of the native serum is so high, and th...

Seed storage proteins are of great importance in nutrition and in industrial transformation because of their functional properties. Brachypodium distachyon has been proposed as a new model plant to study temperate cereals. The protein composition of Brachypodium grain was investigated by separating the proteins on the basis of their solubility combined with a proteomic approach. Salt-soluble pr...

Myotonic dystrophy is a hereditary progressive muscular abnormality with dominant transmittance that was first proposed as a separate entity by Batten and Gibb (1) and by Steinert (2) in 1909. The muscular abnormality that is the dominant feature of the disease is characterized by weakness, wasting, and myotonia, especially of the facial, neck, and distal musculature. Other abnormalities freque...

7S globulins were extracted from common bean (Phaseolus vulgaris L.) seeds and characterized. SDS-PAGE showed major bands corresponding to the phaseolin subunits (43-53 kDa). An amino acid analysis indicated that, in spite of the limited amounts of sulphur amino acids and tryptophan, the globulins contained very high levels of essential amino acids. The protein solubility profiles of native and...

Ditaxis heterantha is a plant of the Euphorbiaceae family that grows in semiarid regions of Mexico. It produces yellow pigmented seeds that are used for coloring of foods. The seeds contain about 20% of proteins. Proteins of D. heterantha were extracted and fractionated on the basis of solubility. Three main protein fractions were obtained: glutelins, 488 ± 0.5; albumins, 229 ± 2; and total glo...

A marked increase of the serum beta globulins was found in rabbits developing amyloidosis as a result of prolonged treatment with ribonucleate administered by subcutaneous injections. Following cessation of treatment the beta globulin levels gradually returned to normal while the gamma globulin levels rose strikingly, the changes being accompanied by a resorption of amyloid from the spleen, and...