Background: Annual screening for CF-related diabetes (CFRD) is recommended from age 10 in the UK. Regular oral glucose tolerance test (OGTT) or Continuous monitoring (CGM) difficult to achieve (35% of patients ≥10 yr had CFRD 2021, UK CF Registry Data). We currently use CGM at and 14 children with clinical concerns. Objective: To evaluate modified control (GCT) children. Methods: GCT was introd...

OBJECTIVE The purpose of the trial was to examine the effects of amantadine, a N-methyl-D-aspartate (NMDA) antagonist, on the oral glucose tolerance test (OGTT) plus insulin, glucagon and neurotransmitters circulating levels. Previous findings showed that hyperinsulinism and type 2 diabetes are positively associated with neural sympathetic and adrenal sympathetic activities, respectively. These...

objective: the high prevalence of gestational diabetes mellitus (gdm) in iran and its maternal and fetal consequences as well as the high risk of its long-term effects including obesity is known. the aim of this study was to evaluate the relationship between body mass index (bmi) in ages of 18 months and 6 years and maternal glucose concentration. materials and methods: this is a retrospective ...

background : this study aimed to compare different body mass index (bmi) categories in individuals with diabetes, prediabetes and normal glucose tolerance among the first degree relatives of type 2 diabetic patients. methods : a cross-sectional study was conducted during 2005-2007 in isfahan, iran. it evaluated 3323 first-degree relatives of diabetic patients selected by consecutive convenient ...

Thirty-six crossbred steers (288 +/- 3.7 kg initial BW) were used to determine the effect of Cr, as chromium-L-methionine, on glucose tolerance and insulin sensitivity in beef calves. Calves were fed a control diet or the diet supplemented with 400 or 800 microg Cr/kg of diet as chromium-L-methionine. Calves were kept in drylots (six calves/pen; two pens/dietary treatment). Steers were caught t...

OBJECTIVE Although screening for diabetes and prediabetes is recommended, it is not clear how best or whom to screen. We therefore compared the economics of screening according to baseline risk. RESEARCH DESIGN AND METHODS Five screening tests were performed in 1,573 adults without known diabetes--random plasma/capillary glucose, plasma/capillary glucose 1 h after 50-g oral glucose (any time,...

AIMS The prevalence of post-challenge hyperglycaemia in coronary patients is high. Until now, it is unclear whether post-challenge hyperglycaemia is associated with an increased risk for future macrovascular events in this clinically important patient population. METHODS AND RESULTS We enrolled 1040 patients undergoing coronary angiography for the evaluation of suspected or established corona...

OBJECTIVE This study tested the hypothesis that a standardized dose of jelly beans could be used as an alternative sugar source to the 50-g glucose beverage to screen for gestational diabetes mellitus. STUDY DESIGN One hundred sixty pregnant women at 24 to 28 weeks' gestation were recruited for a prospective study to compare 2 sugar sources for serum glucose response, side effects, preference...