Previous studies have indicated that blood glucose is the major precursor of both the glucose and galactose moieties of milk lactose. The Cl4 distribution patterns of the two moieties differ, however, and it appears that the glucose and the galactose moieties arise from the different precursors (l-4). It also has been suggested that the unsymmetrical distribution of Cl4 found in the galactose m...

We report the characterization of 6 Leishmania tropica isolates from 2 patients with visceral leishmaniasis who were unresponsive to treatment with sodium stibogluconate. The Leishmania isolates, MHOM/KE/81/NLB-029A, -029XIB, and -029XIC and MHOM/KE/81/NLB-030I, -030B, and -030XXA, all from splenic aspirates, were characterized by cellulose acetate electrophoresis using 11 enzymes: malate dehyd...

OBJECTIVE To determine whether deuterium enrichment on carbons 5 and 3 (C5/C3) in plasma glucose is influenced by processes other than gluconeogenesis and, if so, whether these processes are altered by type 2 diabetes. RESEARCH DESIGN AND METHODS In this study, 10 obese diabetic and 10 obese nondiabetic subjects were infused intravenously with [3,5-(2)H(2)] galactose enriched at a C5-to-C3 ra...

G LUCOSE-PHOSPHATE ISOMERASE (GPI) controls the equilibrium between glucose-6-phosphate (G-6-P) and fructose-6-phosphate (F-6-P). Though G?I does not seem to have a rate-limiting function in red cell glycolysis,’ deficiencies of this enzyme cause hereditary nonspherocytic hemolytic anemia.2 Twelve cases from nine different families have been reported suffering from hemolytic anemia caused by G?...