Licorice botanicals are produced from the roots of Glycyrrhiza species (Fabaceae), encompassing metabolites of both plant and rhizobial origin. The composition in both primary and secondary metabolites (1°/2°Ms) reflects the physiologic state of the plant at harvest. Interestingly, the relative abundance of 1°Ms vs 2°Ms in licorice extracts remains undetermined. A centrifugal partition chromato...

Licorice, the oldest Chinese traditional medicine, is widely used in the treatment of human diseases. Due to the deficiency of wild resource, selecting and breeding becomes a key issue to expanding the supply of licorice. Spaceflight technology will become a new method for medicinal plants. The aim of this study was to investigate the effect of spaceflight on the components and anti-inflammator...

We hypothesized that roasted Glycyrrhizae Radix (Glycyrrhizin Radix Praeparata, GRP) might modify anti-diabetic action due to compositional changes. Then we examined the anti-diabetic effect and mechanism of raw Glycyrrhizae Radix (GR) and GRP extracts and their major respective components, glycyrrhizin and glycyrrhetinic acid. In partial pancreatectomized (Px) diabetic mice, both GR and GRP im...

This study was aimed at evaluating the efficacy of traditional Chinese medicine (TCM) in adjuvant treatment Helicobacter pylori-associated gastritis (HPAG) and exploring molecular mechanism underlying action basic TCM compounds against HPAG. Eight representative British databases were combed for pertinent literature. In light principle evidence-based medicine, this work rigorously stuck to incl...

Abstract The main theme of this research was to screen for tyrosinase inhibition from extracts seven medicinal plants with the aim applying their skin-whitening compounds cosmetic industry. Specifically, botanical parts include Morus alba L. fruit, Pachyrhizus erosus Glycyrrhiza uralensis F. root, Lonicera japonica T. flower, Chrysanthemum indicum Momordica charantia leaf and Carica papaya whic...