We report an instance of critical ovarian hyperstimulation syndrome in a highly responsive in-vitro fertilization patient despite the preventive measure of a 4 day 'coast' interval during which no gonadotrophins were administered while gonadotrophin-releasing hormone agonist therapy continued until serum oestradiol concentrations fell below 3000 pg/ml.

BACKGROUND Ovarian function in Turner syndrome (TS) patients depends on the specific karyotype. This retrospective clinical study evaluates the pituitary-gonadal axis during infancy, childhood and adolescence in TS patients according to karyotype and ovarian function. METHODS A cohort of 70 TS patients (0-16 years) followed at a tertiary referral centre for paediatric endocrinology were inclu...

Background: Azoospermia is the total absence of sperm cells from a patients semen sample after centrifugation. It could be obstructive or non-obstructive and its associated causes include chromosomal defects, infections, gonadotrophins imbalance, and etc in the patients. The objective is to determine the prevalence of primary testicular failure, germinal insufficiency, obstructive azoospermia a...

BACKGROUND To study the short-term biological effect of anastrozole on serum estrogens, androgens, 17-hydroxyprogesterone (17OH-PGR), gonadotrophins, sex hormone binding globulin (SHBG) and bone metabolism markers. MATERIALS AND METHODS Thirty-four consecutive patients with advanced breast cancer received anastrozole 1 mg/day. Blood samples were taken before commencement of treatment and at 2...