BACKGROUND/AIMS The current study examines the expression of molecular biomarkers in hepatocellular carcinoma (HCC) and whether these findings correlate with the clinicopathologic features of the disease and patient survival. METHODS We analyzed the immunohistochemical expression of p53, mammalian target of rapamycin (mTOR), c-Met, and insulin-like growth factor 1 receptor (IGF-1R) heat shock...

OBJECTIVE The objective of this study was to investigate MDM2 (murine double minute 2) protein expression and evaluate its relationship with some anatomical and pathological aspects, aiming also to identify prognostic factors concerning local recurrence-free survival, metastasis-free survival and overall survival in patients with primary liposarcomas of the extremities. MATERIALS AND METHODS ...

a 70 year old male presented with right lower quadrant pain and anorexia for about 72 hours prior to hospital admission. he underwent laparotomy with impression of acute appendicitis. the operative finding was an inflamed tumoral appendix without appendicular base involvement, and appendectomy was done. the patient had an uneventful post-op course. due to the pathology report of prostatic carci...

in patients requiring coronary artery bypass grafting (cabg), usually at least one of the internal mammary arteries is used. this study evaluates the degree of atherosclerotic involvement of the internal mammary artery (ima) in patients undergoing cabg. during two months period, 79 patients (66 male and 13 female with a medium age of 58 years) undergoing myocardial revascularization had a biops...

INTRODUCTION Follicular lymphoma (FL) is an indolent lymphoproliferative disorder of B-cells with variable clinical behavior. It is the second most common subtype of Non-Hodgkin lymphoma in western countries but reported to have a lower incidence in Asia. MATERIALS AND METHODS Cases of FL diagnosed in the Department of Pathology of our Institute from January 2009 to June 2015 were included in...

background: the nutcracker syndrome represents a clinical condition caused by compression of the left renal vein (lrv) between the superior mesenteric artery (sma) and the aorta. one of its manifestations is left-sided varicocele. the aim of this study is to determine the prevalence of nutcracker syndrome in patients with primary and recurrent high grade left-sided varicocele.   methods: fifty ...

OBJECTIVE To describe the incidence of HPV in diffuse high grade pre-cancerous lesions of the larynx. METHODS Patient charts were searched for those who presented between October 2008 and June 2009 with diffuse vocal fold leukoplakia. Biopsy proven laryngeal lesions with high grade dysplasia or carcinoma-in-situ (CIS) were examined for patient characteristics and presence of high-risk type HP...

Bladder cancer is the most common malignancy of urinary tract and the seventh most common cancer in men with the peak incidence in the sixth decade of life. Our knowledge about bladder tumors in pediatric age group mainly relies on case series. The reported cases are mostly low grade and non-muscle invasive. We herein present a case of a 17-year-old male with metastatic high-grade muscle-invasi...