We present an oxygen isotope and petrologic study of four voluminous, zoned ash-flow sheets of the Southwestern Nevada Volcanic Field (SWNVF): Topopah Spring (TS, .1200 km3, 12.8 Ma), Tiva Canyon (TC, 1000 km3, 12.7 Ma), Rainier Mesa (RM, 1200 km3, 11.6 Ma), and Ammonia Tanks (AT, 900 km3, 11.45 Ma). The d18O values of quartz, sanidine, sphene, magnetite, and zircons in rhyolites and latites of...