PURPOSE To report the association of Marcus Gunn jaw-winking phenomenon and pseudo inferior oblique overaction. METHODS Case report. RESULTS A 21-year-old woman presented with right eyelid elevation on the chewing movement since infancy. Examination showed that both Marcus Gunn jaw-winking phenomenon and pseudo inferior oblique overaction coexist in this patient. CONCLUSION The associatio...

THE following case of congenital ptosis with Marcus Gunn phenomenon (Gunn, 1883) is interesting because of its unusual association with multiple paradoxical oculo-palpebral movements (Duke-Elder, 1952). Case Report An 18-year-old girl came for cosmetic correction of a congenital ptosis of the right upper lid with alternate divergent strabismus of about 150. The Marcus Gunn phenomenon was also p...

We present and numerically solve a model of the photorefractive Gunn effect. We find that high field domains can be triggered by phase-locked interference fringes, as it has been recently predicted on the basis of linear stability considerations. Since the Gunn effect is intrinsically nonlinear, we find that such considerations give at best order-of-magnitude estimations of the parameters criti...

We have previously demonstrated that in mice, the decrease in serum thyroxine (T(4)) level by polychlorinated biphenyls (PCBs) occurs without an increase in the UDP-glucuronosyltransferase (T(4)-UDP-GT) for T(4) glucuronidation, although the PCB-induced decrease in rats is generally thought to occur through induction of T(4)-UDP-GT, UGT1A1, and UGT1A6. In the present study, to further clarify t...

Ezetimibe (EZE) selectively blocks intestinal cholesterol absorption by interacting with Niemann-Pick C1 Like 1 (NPC1L1). After administration, EZE is extensively metabolized in liver and intestine to its phenolic glucuronide form (EZE-G) by uridine diphosphate glucuronosyltransferases (UGTs), among which UGT1A1 and 1A3 exhibit highest activity. EZE-G is excreted into bile and undergoes extensi...

1. Reconstitution of purified bilirubin UDP-glucuronyltransferase from Wistar-rat liver into Gunn-rat liver microsomes provides a better environment than phosphatidylcholine liposomes, such that the final specific activity of the Wistar-rat liver enzyme was increased up to 85 units/mg of protein. 2. Gunn- and Wistar-rat liver microsomes were equally effective for reconstitution of the purified ...

Mildly elevated circulating unconjugated bilirubin (UCB) is associated with protection against hypertension and ischemic heart disease. We assessed whether endogenously elevated bilirubin in Gunn rats modifies cardiovascular function and resistance to ischemic insult. Hearts were assessed ex vivo (Langendorff perfusion) and in vivo (Millar catheterization and echocardiography), and left ventric...