AIMS OF THE STUDY Commercially important indigenous medicinal plants of southern Africa are reviewed in the context of fundamental knowledge about their ethnobotany, phylogeny, genetics, taxonomy, biochemistry, chemical variation, reproductive biology and horticulture. The aim is to explore the rapidly increasing number of scientific publications and to investigate the need for further research...

Asperugo procumbents L. has been used in Iranian traditional medicine for the refreshing, tranquillizing and mood elevating activities. The present study was undertaken to evaluate the antidepressant and sedative-hypnotic potential of acute administration of the hydroalcoholic extract of this plant in mice. Additionally, the effects of flumazenil on the hypnotic activity of the extracts were ev...

The aim of this study was to investigate the possible effects Harpagophytum procumbens (HP) extract on pro-inflammatory cytokines, oxidative stress, apoptosis and antioxidant mechanisms in a rat colitis model induced by acetic acid. 40 Wistar albino rats were divided into five equal groups: (1) Control, (2) HP, (3) Colitis, (4) Colitis + (5) Sulfasalazine. Malondialdehyde (MDA), total capacity ...

Osteoarthritis (OA) is a multifactorial disease that can be caused by genetic factors, obesity, joint microtrauma, and excessive physical exercises. The key features of OA include gradual loss articular cartilage, bone tissue remodeling, development osteophytes, subchondral sclerosis. pathogenesis based on the glycosaminoglycans, collagen disorganization, inflammation mediated cytokine cascade....