Attenuation of the GH and insulin-like growth factor I (IGF-I) axis in aging may be responsible for changes in body composition and metabolism. This relationship has been confirmed by studies of recombinant human GH replacement in aging men and women, but the adverse effects encountered limit its clinical utility. The use of GHRH or its analogs may be an alternative mode for restoring the GH-IG...

James Tanner spent much of his childhood abroad, in the baggage train of the British Army; when he was 9 years old the family returned to their home in east Devon and he began his schooling. He attended Marlborough College from 1934 to 1938 on a scholarship reserved for the sons of Army officers. Having specialised first in modern languages and then in mathematics and engineering, he found hims...

IN 1922, an article entitled “On the dominance ratio” appeared in the Proceedings of the Royal Society of Edinburgh. The author was R. A. Fisher, a 29-year-old statistician studying crop variation at the Rothamsted Experimental Station in Harpenden, England. The article was a follow-up to Fisher’s 1918 article on the statistical effects of Mendelian inheritance, but it is in the 1922 article th...

A study was conducted to assess the nutritional status and the prevalence of non-communicable diseases among elderly people in elderly homes in Kandy. A population of 105 elderly people (>65 years), representing 7 elderly homes in Kandy was examined using the Mini Nutritional Assessment (MNA) tool and an additional questionnaire. Skinfold thickness was measured using the Harpenden caliper and b...

This paper reviews some traditional and more recent methods for analyzing unreplicated experiments. Such experiments have presented a challenge to statisticians throughout their involvement in agricultural research. At Rothamsted this began in 1919, when R.A. Fisher was appointed to analyze the accumulated data from the classical field experiments. Fisher’s experiences with the classicals, whic...

This special issue of Bioinformatics contains the proceedings of the ninth European Conference on Computational Biology 2010 (ECCB10), which was held from September 26 to 29 at the International Conference Center in Ghent, Belgium. Details of the conference are available through the conference web site (www.eccb10.org) and will later be archived at eccb.iscb.org/2010. This year’s conference als...

a Rothamsted Research, West Common, Harpenden, AL5 2JQ, England. b Dirección General de Salud Ambiental, Ministerio de Salud, Lima, Peru. Correspondence to Gregor J Devine (e-mail: [email protected]). When no vaccine, prophylaxis or drug treatment exists, insecticides may be the only tools available for combating insect-transmitted diseases such as dengue. They remain the mainstay of most...

“Sequestering Soil Organic Carbon: A Nitrogen Dilemma” W welcome the response by Soussana et al. to our viewpoint article; it is important to have a broad discussion within the scientific community on the feasibility and nature of the 4p1000 goal. In particular, we welcome the explicit acknowledgment that the 4p1000 goal should be recast as “aspirational”, rather than actually achievable in a q...

Soontornvipar t K. , P. Kohout , P. Proks: Septic Arthritis in Dogs: A Retrospective Study of 20 Cases (2000-2002). Acta Vet. Brno 2003, 72: 405-413. Septic arthritis might be difficult to diagnose due to nonspecific clinical signs and radiological findings in early stage of the disease. An early diagnosis is important for achieving favorable prognosis. Diagnosis of septic arthritis was confirm...

Moghadasi, M.; Nuri, R.; Ahmadi, N. Effects of 8 weeks high intensity aerobic exercise on serum retinol binding protein 4 levels in female athletes. Brazilian Journal of Biomotricity. v. 7, n. 1, p. 37-42, 2013. Retinol binding protein 4 (RBP4), has recently been identified as novel adipokines associated with obesity, type 2 diabetes and the metabolic syndrome. The effects of exercise training ...