Acute liver failure (ALF), also known as fulminant hepatic failure (FHF), embraces a spectrum of clinical entities characterized by acute liver injury, severe hepatocellular dysfunction, and hepatic encephalopathy. This condition is uncommon but not rare; it affects approximately 2000 to 2800 people annually in the United States, with a mortality of 3.5 per million despite intensive support. Lo...

Cerebral injury may persist and brain death may occur following an emergency liver transplantation (LT) for fulminant hepatic failure (FHF) even if the graft functions well. We herein present two patients developing brain death following emergency LT for FHF. How to cite this article Akoglu M, Sürmelioglu A, Ozer I, Ercan M, Ulas M, Akdogan M, Bostanci EB. Brain Death after Liver Transplantat...

OBJECTIVE To determine the efficacy of N-acetylcysteine (NAC) in children aged > 1 month to 16 years admitted with Fulminant Hepatic Failure (FHF) secondary to Acute Viral Hepatitis (AVH) in a tertiary care center of a developing country. STUDY DESIGN Analytical study. PLACE AND DURATION OF STUDY Department of Paediatrics, The Aga Khan University Hospital, Karachi, Pakistan, from January 20...

During vertebrate heart development, two progenitor populations, first and second heart fields (FHF, SHF), sequentially contribute to longitudinal subdivisions of the heart tube (HT), with the FHF contributing the left ventricle and part of the atria, and the SHF the rest of the heart. Here, we study the dynamics of cardiac differentiation and morphogenesis by tracking individual cells in live ...

Physically neglected youth are at increased risk of mental health problems, but there are few interventions that have demonstrated efficacy in reducing mental health symptoms for this vulnerable population. The Fostering Healthy Futures (FHF) program, which consists of mentoring and skills groups, was developed for preadolescent youth in foster care. In a published randomized controlled trial w...

Families headed by sexual minorities encounter unique barriers to care and health equity despite greater cultural acceptance and visibility. Empirical research suggests that children in lesbian, gay, bisexual, and transgender (LGBT) families develop and function comparably to those from traditional families. In helping families, awareness of family structure is important. The health care provid...

Nearly 6 million children in the United States today live in households headed by a relative other than their parents. Most of these families are in informal arrangements that do not involve the child welfare system. Child welfare agencies in many states, however, are increasingly relying on relatives, primarily grandparents, to provide both temporary and permanent placements for children who c...

We use newly-available census microdata from IPUMS-International to assess trends in intergenerational coresidence in 15 developing countries. Contrary to expectations, we find no general decline in intergenerational coresidence over the past several decades. There have been, however, significant changes in the configuration of intergenerational coresidence. Families in which the older generati...