Correlation of electrocardiographic abnormalities occurring postoperatively with lesions of the conduction system found at autopsy was done in 20 dogs which had received cardiac homografts. The incidence of arrhythmias closely paralleled the severity of rejection injury found within the heart and specifically within the conduction system. Severe pathological changes in the conduction system (gr...

IT MAY BE CONCLUDED FROM THE RESULTS OBTAINED IN THESE EXPERIMENTS : 1. That stimulation of the right vagus nerve in the dog usually causes arrest of all the chambers of the heart. 2. That stimulation of the left vagus nerve exerts a moderate negative chronotropic effect on the auricles. 3. That stimulation of the left vagus nerve has a profound effect on the conduction of impulses over the aur...

transcatheteraortic valve implantation, first introduced in 2002, has been established as an alternative modality for patients deemed not suitable for open-heart surgery. the anatomical vicinity of the atrioventricular node and the his bundle to the non-coronary and rightcoronary aortic cusps predisposes patients to conduction abnormalities in case of severe calcification or mechanical trauma d...

Correlation of electrocardiographic abnormalities occurring postoperatively with lesions of the conduction system found at autopsy was done in 20 dogs which had received cardiac homografts. The incidence of arrhythmias closely paralleled the severity of rejection injury found within the heart and specifically within the conduction system. Severe pathological changes in the conduction system (gr...

The heart is the first organ required to function during embryonic development and is absolutely necessary for embryo survival. Cardiac activity is dependent on both the sinoatrial node (SAN), which is the pacemaker of heart's electrical activity, and the cardiac conduction system which transduces the electrical signal though the heart tissue, leading to heart muscle contractions. Defects in th...

Study of cardiac dynamics requires analysis of multi-dimensional spatial and temporal variables and complex electromechanical coupling mechanisms. Therefore it requires careful attention to these factors in order to develop a model of the heart that realistically simulates cardiac function. Motion information can be extracted by examining and tracking twoto four-dimensional image data. Electro-...

Retrograde conduction from ventricle to atrium is a well-recognized occurrence in the human heart. The phenomenon has been observed repeatedly during ventricular tachycardia (Kistin, 1961), with ventricular premature and interpolated beats (Kistin, 1959, 1963; Kistin and Landowne, 1951), in patients with ventricular pacemakers (Kastor and De Sanctis, 1967; Barold, Linhart, and Samet, 1968), and...

Approximately 70% of patients with dermatomyositis have evidence of cardiac damage; in one third of cases this affects principally or solely the conduction tissue. In infants similar histological lesions have been associated with a maternal autoantibody, anti-Ro, that crosses the placenta and produces congenital heart block. Anti-Ro antibody was detected in a fatal case of dermatomyositis with ...

The specialized atrioventricular (A-V) conduction system was electrophysiologically delineated during open-heart surgery in four patients with congenitally corrected transposition of the great vessels and associated ventricular septal defect and one patient with single ventricle. Two consistent observations were made: 1) In no case was the specialized A-V conduction system found in the right at...

Specialized fiber electrograms were recorded from selected sites along the His bundle and bundle branches during open-heart surgery in 26 patients. The heart was then paced from the same recording sites. Stimuli applied to the proximal His bundle recording site always resulted in His bundle pacing, which was characterized by a stimulus artifact-to-QRS interval which equaled or very nearly equal...