BACKGROUND Transforming growth factor-β receptor II (TGFBR2) is a key component of TGF-β signaling pathway. TGFBR2 can be detected in the generation of heart. The mouse embryos of TGFBR2 gene knockout exhibited congenital heart defects. METHODS We conducted a case-control study to investigate the association between TGFBR2 gene polymorphisms and congenital heart defects in Han Chinese populat...

conclusions opium has teratogenic effect on cardiovascular system. results from 225 children under study 23.5% had addicted parents based on the variables of the study but the rate was only 2.3 for the control group. the difference between these two groups was significant and the most common form of heart disease was congenital ventricular septal defect. background opium abuse is one of the wid...

In recent years, advances in transcatheter percutaneous closures for adults with congenital heart defects have paralleled technological improvements, including imaging, arrhythmia management, and percutaneous interventions. Indications for percutaneous closure of congenital heart defects have expanded with the widening range of device shapes and sizes. This review gives a brief outline of accom...

BACKGROUND More than 90% of children with congenital heart defects now survive into adulthood; just a few decades ago, survival was rare, particularly among patients with complex defects. The new population of adults with congenital heart disease presents a special challenge to physicians from all of the involved specialties. METHODS Selective literature review. RESULTS AND CONCLUSION A com...

The third edition of Surgery for Congenital Heart Defects proves to be a userfriendly and instructive resource that is sure to be of great value to many physicians. While the seasoned surgeon might call upon the text as a reference, even the greenest medical student wades comfortably into the depths of the text and feels empowered by the visual feast that awaits. As in the previous editions, me...

Bacterial endocarditis is the infection of inner lining of heart and /or heart valves. This disease is usually related to the presence of some pathogenic bacteria in mouth, digestive system or urinary tract. Most of the times, this infection happens in people with heart problems like the presence of prosthetic valves, history of previous endocarditis, some congenital heart defects and heart tra...