Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative option for a variety of malignant and non-malignant hematological and congenital diseases. Due to the fact that the human leukocyte antigen system is inherited independently of the blood group system, approximately 40-50% of all HSCTs are performed across the ABO blood group barrier. The expected immune-hematological conseq...

BACKGROUND Patients treated for hematological malignancies have an increased risk of serious infections. Diagnosis and prompt initiation of therapy are essential. Bronchoalveolar lavage (BAL) is a well-established investigation for identifying the cause of pulmonary infiltrates in immunocompromised patients. The aim of the study was to determine the diagnostic yield of BAL in patients treated f...

We investigated the direct effects of growth hormone (GH) replacement therapy (GH-RT) on hematopoiesis in children with GH deficiency (GHD) with the special emphasis on proliferation and cell cycle regulation. Peripheral blood (PB) was collected from sixty control individuals and forty GHD children before GH-RT and in 3rd and 6th month of GH-RT to measure hematological parameters and isolate CD...

Renal failure is a situation in which kidney fails to function adequately. There are two forms of renal failure: acute and chronic. End-Stage renal disease is the final stage of chronic renal failure where there is a progressive, irreversible deterioration in renal function which can be substituted by renal replacement therapy, haemodialysis (HD), peritoneal dialysis, or transplantation. The ai...

Introduction: The current standard of treatment for locally advanced cancer cervix is cisplatin based concurrent chemo radiation therapy followed by brachytherapy. Concurrent radiotherapy causes acute hematological toxicities, which in turn leads to prolongation therapy. Objective: main purpose our study, was analyze the toxicity cervical patients undergoing or Materials and Methods: This a hos...

Summary Myeloproliferative neoplasms (MPN) are clonal hematological conditions characterized by excessive production of one or more cell lines in the bone marrow. The blood cells produced often hyperactive their functions, which could lead to complications disorder‘s clinical course. We aimed define role granulocytic CD11b/CD18 expression for thrombotic risk MPN patients. investigated 110 patie...

PURPOSE Natural history and consequences of the novel 2009 influenza A H1N1 (2009 H1N1) infection in immunocompromised pediatric patients are not yet fully understood. In this study, we investigated the clinical features and outcomes of the 2009 H1N1 infection in pediatric patients with hematological and oncological diseases. METHODS We retrospectively reviewed the medical records of 528 pati...

Aplastic Anemia is a rare hematological disorder caused by bone marrow failure leading to pancytopenia. These patients are frequently treated with immunosuppressive therapy which may protect them in developing hyper-inflammatory response commonly seen moderate and severe COVID-19 patients. On the other hand these at high risk for infection related complications. Here we reporting an adult aplas...

INTRODUCTION Piperacillin/tazobactam is a commonly used antibiotic for the empirical treatment of severe diabetic foot infections. One of the most feared complications of this drug is the development of pancytopenia. The aim of this study was to determine whether the use of piperacillin/tazobactam caused any hematological changes in patients admitted with severe diabetes-related foot infections...