Background: Development of locally-derived hematological reference intervals is necessary for improving the quality of health care and clinical trials. However hematological reference intervals are affected by several variables including age, gender and environmental factors. Therefore this study was conducted to determine the gender and age-specific hematological reference intervals of healthy...

OBJECTIVE Copper deficiency has been reported to cause hematological disorders. However, its clinical and hematological characteristics are not fully understood. Therefore, we investigated bedridden patients suffering from copper deficiency and tried to clarify the clinical features of hematological disorders caused by this condition. PATIENTS AND METHODS Five patients with typical copper def...

Malaria is an epidemiological problem at the global level. In Indian sub continent it is a major cause of mortality in immunosupressed patients and in extreme ages of life. Our study is based on early detection of malaria by hematological parameters. A study on 287 malaria patients was carried out at P.D.U Medical College, Rajkot between 1st July 2009 to 31st December 2009 with an objective to ...

In recent years, advances in next-generation sequencing (NGS) technology have provided the opportunity to detect putative genetic drivers of disease, particularly cancers, with very high sensitivity. This knowledge has substantially improved our understanding of tumor pathogenesis. In hematological malignancies such as acute myeloid leukemia and myelodysplastic syndromes, pioneering work combin...

The present study focused on the chemical characterization of PITC-2 (2-(prop-1-ynyl)-5(5,6-dihydroxyhexa-1, 3-diynyl)-thiophene, a thiophen derivative) isolated from the root extract of tissue-cultured medicinal plant Pluchea indica (L.) Less. Evaluation of sub-acute toxicity study of the new compound was also done in vivo. Methanolic root extract of tissue-cultured P. indica was separated by ...

OBJECTIVE To diagnose iron deficiency anemia in children. METHODS The study was conducted with a sample of 301 children aged six to 30 months attending public daycare centers in the city of Recife, Northeast Brazil, in 2004. The diagnoses of anemia were based on a combination of different hematological and biochemical parameters: hemoglobin, mean corpuscular volume, ferritin, C-reactive prote...

There has been a notable increase in the area of field herbal medicine. The medicinal herbs and crops are gaining popularity developing developed countries because their natural origin fewer side effects.The current study investigated Spondiasmombins phytochemical content its effect on Red Blood Cells Monosodium Glutamate (MSG) induced fibroid experimental rats. animals were grouped into three ...

Constitutional pericentric inversion of chromosome 9 [inv(9)] occurs in 0.8 to 2% of the normal population and has long been considered a normal variant. It is controversial whether inv(9) is a predisposing factor for acute leukemia (AL). The effect of inv(9) on bone marrow (BM) recovery after stem cell transplantation or chemotherapy is undetermined. Between March 2001 and December 2008, the c...

TO THE EDITOR: In their recent editorial on the disappointing disagreement between two World Anti-Doping Agency (WADA)-accredited laboratories evaluating samples for detecting recombinant human erythropoietin (Epo) in urine, Delanghe and Joyner (4) concluded that blood-based indirect Epo tests offer an interesting alternative (2). This is ideally true, considering that the urine test is proven ...