نتایج جستجو برای: hemozoin

تعداد نتایج: 384  

2011
Nguyen Thanh Thuy Nhien Nguyen Tien Huy Dinh Thanh Uyen Eric Deharo Pham Thi Le Hoa Kenji Hirayama Shigeharu Harada Kaeko Kamei

Heme detoxification through crystallization into hemozoin has been suggested as a good target for the development of screening assays for new antimalarials. However, comparisons among the data obtained from different experiments are difficult, and the IC(50) values (the concentrations of drug that are required to inhibit 50% of hemozoin formation) for the same drug vary widely. We studied the e...

Journal: :Accounts of chemical research 2014
Leeor Kronik Alexandre Tkatchenko

CONSPECTUS: Molecular crystals are ubiquitous in many areas of science and engineering, including biology and medicine. Until recently, our ability to understand and predict their structure and properties using density functional theory was severely limited by the lack of approximate exchange-correlation functionals able to achieve sufficient accuracy. Here we show that there are many cases whe...

Journal: :Molecular and biochemical parasitology 2000
M F Oliveira J C d'Avila C R Torres P L Oliveira A J Tempone F D Rumjanek C M Braga J R Silva M Dansa-Petretski M A Oliveira W de Souza S T Ferreira

a Departamento de Bioquı́mica Médica, Uni6ersidade Federal do Rio de Janeiro, Cidade Uni6ersitária, 21941-590, Rio de Janeiro, RJ, Brazil b Di6isão de Quı́mica, Setor de Quı́mica Orgânica, CENPES, Petrobrás, Cidade Uni6ersitária, 21949-900, Rio de Janeiro, RJ, Brazil c Centro de Biociências e Biotecnologia, Uni6ersidade Estadual do Norte Fluminense, Campos dos Goytacazes, RJ, 28015-620, Brazil d I...

Journal: :Advances in Pharmacological Sciences 2014

Journal: :Molecular and Biochemical Parasitology 1994

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