Anti-idiotype reagents that recognize a common idiotype associated with the combining site of antibodies to hepatitis B surface antigen (anti-HBs) were used to manipulate the immune response to hepatitis B surface antigen in BALB/c mice. The injection of antibodies to the idiotype before antigenic stimulation resulted in an increase in the number of cells secreting immunoglobulin M antibodies t...

Submit Manuscript | http://medcraveonline.com Abbreviations: 95%CI: 95% Confidence Interval; ANC: Antenatal Care Attendee; aOR: Adjusted Odds; Ratio; cOR: Crude Odds Ratio; HBV: Hepatitis B Virus; HBeAg: Hepatitis B e antigen; HBsAg: Hepatitis B Surface Antigen; Anti-HBc: Hepatitis B Core Antibody; Anti-HBe: Hepatitis Be Antibody; Anti-HB: Hepatitis B Surface Antibody; HIV: Human Immunodeficien...

Submit Manuscript | http://medcraveonline.com Abbreviations: 95%CI: 95% Confidence Interval; ANC: Antenatal Care Attendee; aOR: Adjusted Odds; Ratio; cOR: Crude Odds Ratio; HBV: Hepatitis B Virus; HBeAg: Hepatitis B e antigen; HBsAg: Hepatitis B Surface Antigen; Anti-HBc: Hepatitis B Core Antibody; Anti-HBe: Hepatitis Be Antibody; Anti-HB: Hepatitis B Surface Antibody; HIV: Human Immunodeficien...

By using an amplification-created restriction site method, the precore TAG mutant of hepatitis B virus was detected in 6 (75%) of 8 acute fulminant hepatitis B patients, 7 (58%) of 12 acute self-limiting hepatitis B patients, 35 (81%) of 43 hepatitis B virus surface antigen carriers with fulminant hepatitis, and 42 (70%) of 60 hepatitis B virus surface antigen carriers with chronic hepatitis. T...

Background and Aims: Evaluation of the prevalence of transfusion-transmissible infections (TTIs) in blood donors is a valuable index of donor selection and blood safety. This study was conducted to explore the prevalence and trends of TTIs markers and study of confidential unit exclusion )CUE) option among blood donors in Kurdistan province in the west of Iran. Materials and Methods: We conduc...

Background Occult hepatitis B infection (OBI) is considered a risk factor for progression of liver disease in patients with hepatitis B virus (HBV) infection. This disease progression is reported to be more significant in those with concomitant HIV infection. We aimed to determine the prevalence rate of OBI in a sample of HIV-positive patients. Materials and Methods: Sixty-six HIV-infected pati...

Submit Manuscript | http://medcraveonline.com Abbreviations: HBV: Hepatitis B Virus; HBs Ag: Hepatitis B Surface Antigen; HBe Ag: Hepatitis B e Antigen; anti-HBe Ab: Hepatitis B e Antibodies; HCC: Hepatocellular Carcinoma; HDV: Hepatits Delta Virus; GGT: Gamma-Glutamyl Transpeptidase; ALP: Alkaline Phosphatase; ALT: Alanine Aminotransferase; AST: Aspartate Aminotransferase; AFP: Alpha Foeto-Pro...

Background: Although regular frequent blood transfusion improves overall survival of multi-transfused patients like β-thalassemic ones, it carries a definite risk of infection with blood-borne viruses such as viral hepatitis. This study was done to determine seropositivity of hepatitis B virus (HBV), hepatitis C virus (HCV), and Human Immunedeficiency Virus (HIV) infections among β-th...

The goal of antiviral therapy for chronic hepatitis B is to prevent the development of cirrhosis and hepatocellular carcinoma. End points, including viral suppression, alanine aminotransferase normalization, hepatitis B e antigen loss, hepatitis B surface antigen loss, and improvement in liver histology, are used to determine treatment success. Treatment is based on hepatitis B virus (HBV) repl...