There is widespread human exposure to peroxisome proliferators, which are structurally diverse compounds. Peroxisome proliferators received their name based on their ability to induce proliferation of w x peroxisomes in rodent hepatocytes 1 ; they include hypolipidemic drugs, phthalates, steroids, herbicides, w x and solvents 2 . Despite their structural diversity, these compounds induce predic...