The present study is aimed to evaluate the hepatoprotective effects of leaves and flower extracts of ervatamia coronaria against CCl4 induced hepatic damage. The results indicated that both flower and leaves extract of ervatamia coronaria exhibited significant effect against CCl4 induced hepatic damage. We also observed the restoration of elevated levels liver marker enzymes includes SGOT,SGPT,...

Objective: To evaluate the hepatoprotective activity of Pterocarpus marsupium stem bark extracts against carbon tetrachloride (CCl 4 )-induced hepatotoxicity. Materials and methods: Hepatotoxicity was induced in male Wistar rats by intraperitoneal injection of CCl 4 (0.1 ml/kg/day for 10 days). Methanol and aqueous extracts of P. marsupium stem bark were administered to the experimental rats (2...

Hepatic toxicity is the most serious adverse effect of anti-tuberculosis drugs. This study was performed to evaluate the efficacy of silymarin as a hepatoprotective herbal agent. In a randomized double blind clinical trial, 70 new cases of pulmonary tuberculosis were divided into two groups. The intervention group was assigned to receive silymarin and the control group received placebo. Tubercu...

The ethanolic extract of the root of Vitis vinifera (Vitaceae) was evaluated for hepatoprotective activity in rats with liver damage induced by carbon tetrachloride. The extract at an oral dose of 200 mg/kg exhibited a significant protective effect by lowering the serum levels of SGPT, SGOT, alkaline phosphatase and total bilirubin. The extract at this dose also increases the level of total pro...

The present study was carried out to evaluate the hepatoprotective and antioxidant effect of the methanol extract of Caesalpinia bonducella (MECB) (Family: Caesalpiniaceae) in Wistar albino rats. The different groups of animals were administered with carbon tetrachloride (CCl4) (30 % CCl4, 1 ml/kg b. wt. in liquid paraffin 3 doses (i.p.) at 72 h interval). The MECA at the doses of 50, 100 and 2...

Hepatic disease (Liver disease) is a term for a collection of conditions, diseases, and infections that affect the cells, tissues, structures, or functions of the liver. Liver has a wide range of functions, including detoxification, protein synthesis, and production of biochemical necessary for digestion and synthesis as well as breakdown of small and complex molecules, many of which are necess...

Six triterpene acids identified as betulinic, oleanolic, ursolic, 3-epimaslinic, alphitolic and euscaphic acids have been isolated from a dichloromethane extract of hairy root cultures of Ocimum basilicum L. (Lamiaceae). These cultures were obtained by genetic transformation using Agrobacterium rhizogenes. The extract as well as the isolated compounds were evaluated for their hepatoprotective a...

BACKGROUND The effectiveness of hepatoprotective drugs for DIH (drug induced hepatotoxicity) during tuberculosis treatment is not clear. We evaluated the effectiveness of hepatoprotective drugs by comparing the period until the normalization of hepatic enzymes between patients who were prescribed with the hepatoprotective drugs after DIH was occurred and patients who were not prescribed with th...

Hepatic toxicity is the most serious adverse effect of anti tuberculosis drugs. This study was performed to evaluate efficacy of silymarin as a hepatoprotective herbal agent. In a randomized double blind clinical trial 70 new cases of pulmonary tuberculosis were divided into two groups. The intervention group was assigned to receive silymarin and the control group received placebo. Tuberculosis...

Hepatic toxicity is the most serious adverse effect of anti tuberculosis drugs. This study was performed to evaluate efficacy of silymarin as a hepatoprotective herbal agent. In a randomized double blind clinical trial 70 new cases of pulmonary tuberculosis were divided into two groups. The intervention group was assigned to receive silymarin and the control group received placebo. Tuberculosis...