Herpes Simplex Viruses (HSV) viruses are highly contagious that commonly cause dermatitis, encephalitis, meningitis and genitourinary infections also can lead to cervical cancer. For treatment of HSV infections, several physical methods antiviral drugs introduced, medications prevent or reduce outbreaks. The use herbal medicine with effects attracted worldwide attentions. aim this review articl...

Acute infectious encephalitis is a rare neurological pathology with varied etiology and serious prognosis. The purpose of this work to report the experience pediatric diseases department Childrens Hospital Rabat in management condition order identify clinical, paraclinical, etiological, therapeutic evolutionary determine prognostic factors. Materials Methods: This retro-prospective monocentric ...

Aspergillosis 1/1 Astrocytoma/glioblastoma 3/3 2 (1–3) Bacterial meningitis — 7/10 CMV encephalitis — 49/54 CMV plus other OI 5/23 Cryptococcosis 6/45 2 (1–4) 67/263 Encephalopathy, unknown origin 6/7 1 (1–2) 36/41 Herpetic meningoencephalitis — 8/10 HIV encephalopathy — 74/87 HIV encephalopathy plus other OI 2/3 Primary brain lymphoma 15/16 1 (1–2) — PML 67/78 Syphilis — 11/14 Systemic non-Hod...

Herpes simplex virus is a common virus that causes a variety of clinical presentations ranging from mild to life-threatening. Orolabial and genital herpes are common disorders that can often be managed in an outpatient setting; however, some patients do present to the emergency department with those conditions, and emergency clinicians should be aware of possible complications in the pediatric ...

Herpes simplex virus-1 (HSV-1) is a double-stranded DNA virus that causes life-long infections. HSV-1 infections may lead to herpetic stromal keratitis that may advance to corneal blindness. HSV-1 infections can also cause fatal conditions, such as herpes encephalitis, or neonatal disease. A major virulence mechanism of HSV-1 is the control of autophagy, an innate immune defense strategy that c...

Topical application of 1-beta-d-ribofuranosyl-1,2,4-triazole-3-carboxamide (Virazole) significantly inhibited the development of herpetic keratitis in the eyes of rabbits, as determined by both infectivity and Draize scoring parameters. Significant inhibition of the infection was demonstrated with 10% concentrations of Virazole; a 1% solution had a moderate effect, whereas doses of 0.1 and 0.01...

The presence of balloon cells, a pathognomonic cellular feature of focal cortical dysplasia type IIB, in a background of hippocampal sclerosis is rare. Here we report the surgical pathologic features of the hippocampus resected from a 32-year-old woman with mesial temporal lobe epilepsy and a precipitating history of non-herpetic acute limbic encephalitis. Histologically, the resected specimen ...

Forty patients with disciform keratitis were randomly assigned to double-blind treatment with 3% acyclovir and 0.01% betamethasone drops or acyclovir and matching placebo. All patients who received the combination healed in a median time of 21 days, while 11 of 19 patients who received acyclovir alone were withdrawn because their condition remained static or worsened (p less than 0.001). The co...