نتایج جستجو برای: high throughput sequencing

تعداد نتایج: 2174982  

Journal: :Medycyna Weterynaryjna 2022

High throughput sequencing (HTS) creates an opportunity for comprehensive genomic studies. It can be applied in veterinary science, bacteriology and virology, diagnostics of animal diseases, food safety, examinations the composition environmental samples, even vaccinology. Thus HTS a wide-ranging method that different areas One Health approach. In particular, whole genome (WGS) bacteria is rout...

2016
Avi Z. Rosenberg Michael D. Armani Patricia A. Fetsch Liqiang Xi Tina Thu Pham Mark Raffeld Yun Chen Neil O’Flaherty Rebecca Stussman Adele R. Blackler Qiang Du Jeffrey C. Hanson Mark J. Roth Armando C. Filie Michael H. Roh Michael R. Emmert-Buck Jason D. Hipp Michael A. Tangrea

Precision medicine promises to enhance patient treatment through the use of emerging molecular technologies, including genomics, transcriptomics, and proteomics. However, current tools in surgical pathology lack the capability to efficiently isolate specific cell populations in complex tissues/tumors, which can confound molecular results. Expression microdissection (xMD) is an immuno-based cell...

Journal: :Briefings in bioinformatics 2013
Jing Wang Patricia A. McLenachan Patrick J. Biggs Linton H. Winder Barbara I. K. Schoenfeld Vinay V. Narayan Bernard J. Phiri Peter J. Lockhart

There is much interest in using high-throughput DNA sequencing methodology to monitor microorganisms, complex plant and animal communities. However, there are experimental and analytical issues to consider before applying a sequencing technology, which was originally developed for genome projects, to ecological projects. Many of these issues have been highlighted by recent microbial studies. Un...

Journal: :The Journal of eukaryotic microbiology 2015
Sarah K Hu Zhenfeng Liu Alle A Y Lie Peter D Countway Diane Y Kim Adriane C Jones Rebecca J Gast S Craig Cary Evelyn B Sherr Barry F Sherr David A Caron

Sequencing hypervariable regions from the 18S rRNA gene is commonly employed to characterize protistan biodiversity, yet there are concerns that short reads do not provide the same taxonomic resolution as full-length sequences. A total of 7,432 full-length sequences were used to perform an in silico analysis of how sequences of various lengths and target regions impact downstream ecological int...

2015
Enrico Siragusa

Over thepast years, high-throughput sequencing (HTS)hasbecomean invaluablemethod of investigation in molecular and medical biology. HTS technologies allow to sequence cheaply and rapidly an individual’s DNA sample under the form of billions of short DNA reads. The ability to assess the content of a DNA sample at base-level resolution opens the way to a myriad of applications, including individu...

2013
Wendy Weijia Soon Manoj Hariharan Michael P Snyder

Advances in genome sequencing have progressed at a rapid pace, with increased throughput accompanied by plunging costs. But these advances go far beyond faster and cheaper. High-throughput sequencing technologies are now routinely being applied to a wide range of important topics in biology and medicine, often allowing researchers to address important biological questions that were not possible...

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