background and objectives: multiple sclerosis is an inflammatory disease of the central nervous system. this is due to migration of peripherally activated lymphocytes to central nervous system leading to inflammatory lesions. however, liver has an anti-inflammatory microenvironment. myelin expression in the liver of transgenic mice suppresses inflammatory lesions within central nervous system. ...

objective: salmonellosis is a bacterial disease with a rising prevalence in the cattle industry. it is most common in dairy calves one to ten weeks of age. salmonellosis has a serious economic impact on the cattle industry worldwide. methods: in may 2013, a three months old male holstein calf with the history of lateral recumbency was referred to veterinary hospital with severe depression, cach...

Disparate innate immune responses to persistent and acute Chlamydia pneumoniae infection in COPD Daniel Droemann1, Jan Rupp2, Torsten Goldmann3, Ulrike Uhlig4, Detlev Branscheid5, Ekkehard Vollmer3, Peter Kujath6, Peter Zabel1,7, Klaus Dalhoff7 1Medical Clinic, Research Center Borstel, 23845 Borstel, Germany 2Institute of Medical Microbiology and Hygiene, University of Schleswig-Holstein, Campu...

Silica boron sulfonic acid [SiO2–B(OSO3H)3] as an inexpensive, reusable, and Lewis and Brønsted acid catalyst was successfully synthesized, and used for the one-pot three-components synthesis of biologically active substituted Hantzsch 1,4-dihydropyridine derivatives  in the absence of solvent at 90ºC. Silica boron sulfonic acid is attractive and efficient, because it plays in two role as a Lew...

BACKGROUND Peripheral nerve sheath tumors (PNSTs) are frequently found in Danish cattle at slaughter. Bovine PNSTs share several gross and histopathological characteristics with the PNSTs in humans with heritable neurofibromatosis syndromes. The aim of the present study was to investigate a possible hereditary disposition to PNSTs in dairy cattle by statistical analysis performed on data from 5...

Jockusch showed that 2-generic degrees are downward dense below a 2-generic degree, but in the case of 1-generic degrees Kumabe, and independently Chong and Downey constructed a minimal degree computable from a 1-generic degree. We explore the tightness of these results. We solve a question of Barmpalias and Lewis-Pye by constructing a minimal degree computable from a weakly 2-generic one. The ...