Polycystic ovary syndrome (PCOS), the most common endocrinopathy in women (with a prevalence of 5-10 %), is characterized by hormonal and metabolic imbalance. Complexity of symptoms of close relatives of women with PCOS and genetic autosomal trait initiated a hypothesis about the existence of a male equivalent of PCOS. Premature alopecia was suggested as one of the signs of a male phenotype of ...

We review recent evidence that suggests that hormonal contraceptives may influence the dynamics of sexual relationships and the human pair-bond. Hormonal contraception likely has positive effects on cementing the pair-bond by decoupling sex from conception. However, changes in women’s evolved mate preferences associated with initiation or discontinuation of hormonal contraception may alter attr...

Hormonal contraception is the most widely used method to prevent unplanned pregnancies. The literature has shown an association between cardiovascular risk and use of hormone therapy. With the purpose of providing better guidelines on contraception methods for women with risk factors for cardiovascular disease, we have reviewed the literature on the subject. This review describes the latest dat...

OBJECTIVE To determine the impact of hormonal contraceptive methods on risk of HIV acquisition among HIV-negative women cohabiting with HIV-positive male partners. STUDY DESIGN From 1994-2012, HIV discordant couples recruited from a couples' voluntary HIV counseling and testing center in Lusaka, Zambia were followed longitudinally. HIV-negative partners were tested quarterly. This analysis is...

AIM To determine antiandrogen effects on muscle strength gain and fat-free mass increase during exercise in women using hormonal contraception with antiandrogen content. METHODS The study included 50 women (age range, 18-30 years; mean-/+SD, 26-/+3) using hormonal contraception for at least 12 months before the beginning of the study. They were divided into two groups: "antiandrogen" group (n...

OBJECTIVE To summarize published evidence on drug interactions between hormonal contraceptives and antiretrovirals. DESIGN Systematic review of the published literature. METHODS We searched PubMed, POPLINE, and EMBASE for peer-reviewed publications of studies (in any language) from inception to 21 September 2015. We included studies of women using hormonal contraceptives and antiretrovirals...

Currently, Contraceptive agents play a key role in family planning in India. Hormonal contraception is the marketed most common birth control option in women. An estimated 100 million women throughout the world use hormonal contraceptives for prevention of pregnancy. This article briefly describes the recent advances in hormonal contraceptive strategies that may minimize side effects while opti...

Hormonal manipulation plays a significant role in the treatment of advanced hormone naïve prostate cancer and castration-resistant prostate cancer (CRPC) with or without previous chemotherapy. Combination of gonadotropin releasing hormone (GnRH) agonists and androgen receptor (AR) antagonists (combined androgen blockade; CAB) is the first line therapy for advanced hormone naïve prostate cancer,...

Each year in the United States about 1 in 20 women experiences an unintended pregnancy. Understanding the impact of consistent, appropriate, and effective contraception on this major health care concern is key to overcoming this societal and economic burden. In addition to available family-planning services, women need ongoing support in choosing and using methods based on her overall life situ...

PURPOSE OF REVIEW Adjuvant and salvage radiotherapy after radical prostatectomy have an established role in the management of high-risk patients. We discuss contemporary data on optimal timing and doses of radiotherapy, role of hormonal therapy and pelvis irradiation, and toxicity. RECENT FINDINGS Positive surgical margins are not predictive of reduced overall survival, even in patients treat...