نتایج جستجو برای: host pathogen interaction
تعداد نتایج: 806653 فیلتر نتایج به سال:
Candida albicans, the major invasive fungal pathogen of humans, can cause both debilitating mucosal infections and fatal invasive infections. Understanding the complex nature of the host-pathogen interaction in each of these contexts is essential to developing desperately needed therapies to treat fungal infections. RNA-seq enables a systems-level understanding of infection by facilitating comp...
The interaction of bacterial pathogens with mammalian hosts leads to a variety of physiological responses of the interacting partners aimed at an adaptation to the new situation. These responses include multiple metabolic changes in the affected host cells which are most obvious when the pathogen replicates within host cells as in case of intracellular bacterial pathogens. While the pathogen tr...
Relatively little is understood about the dynamics of global host-pathogen transcriptome changes that occur during bacterial infection of mucosal surfaces. To test the hypothesis that group A Streptococcus (GAS) infection of the oropharynx provokes a distinct host transcriptome response, we performed genome-wide transcriptome analysis using a nonhuman primate model of experimental pharyngitis. ...
Vector-borne disease transmission is a common dissemination mode used by many pathogens to spread in a host population. Similar to directly transmitted diseases, the within-host interaction of a vector-borne pathogen and a host's immune system influences the pathogen's transmission potential between hosts via vectors. Yet there are few theoretical studies on virulence-transmission trade-offs an...
Pathogens have evolved unique mechanisms to breach the cell surface barrier and manipulate the host immune response to establish a productive infection. Proteins exposed to the extracellular environment, both cell surface-expressed receptors and secreted proteins, are essential targets for initial invasion and play key roles in pathogen recognition and subsequent immunoregulatory processes. The...
One of the properties of systemically acquired resistance in plants is their concomitance with the biochemical changes including enhancement of activities of defense-related enzymes. The leaf extract of Reynoutria sachalinensis (F. Schmidt) Nakai is known to be an effective compound for the control of a few plant diseases particularly powdery mildew of cucurbits (caused by fungal pathogen Podos...
One of the properties of systemically acquired resistance in plants is their concomitance with the biochemical changes including enhancement of activities of defense-related enzymes. The leaf extract of Reynoutria sachalinensis (F. Schmidt) Nakai is known to be an effective compound for the control of a few plant diseases particularly powdery mildew of cucurbits (caused by fungal pathogen Podos...
www.sciencedirect.com Microbial infections are characterized by a continual dramatic interplay between pathogen and host: pathogens exploit an array of host cell functions during infection and their hosts respond with appropriate immune responses. Host–pathogen interactions are complex and dynamic by nature and are generally analyzed with a reductionist approach focusing on one facet of the int...
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