Introduction: This is a prospective study of patients treated for a solitary toxic nodule with a fixed dose of radioiodine ( I) and followed for at least 1 year in Mashhad, north east of Iran. 131 Methods: We evaluated 780 patients who presented to the university hospital of Ghaem during a 7-year period because they had at least one thyroid nodule. We found hot thyroid nodules in 95 (12%) patie...

▼ Thyroid cancer can be associated with thyrotoxicosis caused by Graves’ disease, toxic multinodular goiter, or autonomously functioning thyroid adenoma. The objective of this study was to summarize current evidence regarding the association of thyroid cancer and hyperthyroidism, particularly with respect to the type of hyperthyroidism found in some patients, and whether this aff ects the outco...

Primary cutaneous CD30+ T cell lymphoma is rare lymphoma originally in and confined to the skin. These lymphomas usually present as a large solitary and often ulcerated nodule. Its prognosis is a good and has a good response to radiotherapy. We report a 34- year- old man who had primary cutaneous CD30+T cell lymphoma on his face, which presented as an ulcerated nodule.

Sister Mary Joseph Nodule is an eponymous term referring to umbilical nodule harbouring malignant metastatic cancer. It a physical finding that uncommon yet significant since it indicates the late manifestation of variety deep-seated abdominopelvic malignancies. This review article briefly revisits historical background, epidemiology, anatomical routes metastasis, clinical presentation, differe...

We present a case of hepatocellular carcinoma (HCC), showing an atypical "nodule-in-nodule" appearance on ultrasonogram (US). In general, a "nodule-in-nodule" appearance is found as a hyperechoic tumor containing a hypoechoic nodule. In the present case, however, there was a hyperechoic subnodule in the center of the tumor, which was surrounded by a hypoechoic tumor area. Histologically, the su...

Metastatic cancer of the umbilicus, known as Sister Mary Joseph nodule, is typically associated with visceral malignancy. It is an uncommon and rare presentation. It indicates disseminated disease and poor prognosis. Physicians need to be aware of this rare clinical condition so that they can promptly diagnose the primary cancer.

PURPOSE To determine the prevalence, clinical characteristics and nature of subfoveal nodules in Coats' disease and the associated impact on the long-term visual outcome. METHODS Consecutive cases of Coats' disease with foveal exudation were retrospectively reviewed. The presence of a subfoveal nodule or macular fibrosis was recorded. Clinical characteristics, retinal imaging, and outcome wer...

background: sonoelastography is a new ultrasound method which could be helpful to determine which thyroid nodule is malignant. we designed this study to evaluate the accuracy of sonoelastography in differentiating of benign and malignant thyroid nodules in iranian patients. methods: forty thyroid nodules in forty consecutive patients who had been referred for sonography‑guided fine‑needle aspir...

377 patients with single thyroid nodule who clinically were candidates for surgery, were selected from the patients that referred to the clinics of endocrinology at namazee hospital, shiraz medical school. fine needle aspiration (fna) was carried out without performing thyroid scan and the results were compared with histology obtained by surgery to establish its accuracy in our center. which is...

introduction: a thyroid nodule is a palpable swelling in a thyroid gland with an otherwise normal appearance. palpable thyroid nodules occur in 4 to 7 percent of the population. nodular thyroid diseases are more frequent in women than in men. most actions of thyroid hormone are mediated by the active form of thyroid hormone. d2 is essential for formation of active hormone of t3 through deiodina...