Erythropoietin (EPO), the main growth factor responsible for the regulation of red blood cell production, may be overproduced when blood loss or haemolysis occurs. Patients with mild hereditary spherocytosis (HS) are able to maintain normal haemoglobin concentration, whereas typical and severe HS patients develop an anaemic state. Splenectomy usually reverses anaemia. We aimed to clarify the ro...

Heparan sulfate (HS) proteoglycans comprising HS glycosaminoglycan chains (HS-chains) and core proteins function in the membrane and extracellular matrix (ECM) as co-receptors for growth factors; i.e., they modulate activity of signaling factors via controlling their extracellular stabilization and movement. However, precise mechanisms by which HS-chains regulate complex mammalian morphogenetic...

The present study was aimed at elucidating the effects of supplementing mannan-oligosaccharides (MOS) and probiotic mixture (PM) on growth performance, intestinal histology, and corticosterone concentrations in broilers kept under chronic heat stress (HS). Four hundred fifty 1-d-old chicks were divided into 5 treatment groups and fed a corn-soybean diet ad-libitum. The temperature control (CONT...

OBJECTIVES This paper explores the role of race/ethnicity in the occurrence of early childhood caries (ECC) among California Head Start (HS) and non-HS preschool children. METHODS Using oral examination and questionnaire data from the 1993-94 California Oral Health Needs Assessment of Children, we computed the prevalence of ECC using various definitions and fitted logistic regression models t...

Dextransucrase and invertase of some strains of Streptococcus mutans were examined by immunodiffusion with antisera against enzymes purified from strain HS-6 (Bratthall's serotype a). Both antisera cross-reacted with crude enzyme preparations from the other serotype a (strains HS-1 and AHT) and d organisms (strains KIR, OMZ176, and OMZ65) but not with those from serotype b (strains FA-1 and BHT...

Heparan sulfate (HS) proteoglycans comprising HS glycosaminoglycan chains (HS-chains) and core proteins function in the membrane and extracellular matrix (ECM) as co-receptors for growth factors; i.e., they modulate activity of signaling factors via controlling their extracellular stabilization and movement. However, precise mechanisms by which HS-chains regulate complex mammalian morphogenetic...

Inhalation of hypertonic saline (HS) acutely enhances mucociliary clearance (MC) in both health and disease. In patients with cystic fibrosis (CF), repeated use of HS causes a sustained improvement in MC as well as clinical benefit. The pharmacodynamic duration of activity on MC may be an important determinant of its therapeutic potential in other airways diseases. Before moving toward testing ...

Heparan sulfate (HS) polysaccharides are ubiquitous in animal tissues as components of proteoglycans, and they participate in many important biological processes. HS carbohydrate chains are complex and can contain rare structural components such as N-unsubstituted glucosamine (GlcN). Commercially available HS preparations have been invaluable in many types of research activities. In the course ...

The first examples of trinuclear complexes of any dipyridyltriazole, [Fe(II)(3)(Rdpt)(4)(NCS)(6)], are, respectively: [HS-HS-HS] when Rdpt = phdpt and "[LS-HS-LS]" when Rdpt = ibdpt.