Rhesus monkeys were immunized with normal human lymphoid cells, cultured lymphoid cells, and chronic leukemic lymphocytes. Antisera were analyzed by cytotoxicity and immunofluorescence techniques to study the antigenic characteristics of human lymphocytes. In an attempt to obtain a reagent specifically reactive with T (thymus-derived) lymphocytes, an antispleen antiserum was absorbed with cellf...

The Apo-1/Fas antigen (CD95) mediates programmed cell death of lymphocytes when bound by Fas ligand or anti-Apo-1/Fas antibody. In contrast, the CD40 antigen provides a potent activation and survival signal to B lymphocytes when it is engaged by its T cell ligand (CD40L, gp39) or cross-linked by anti-CD40 antibody. In this study, we use human tonsillar B cells and the Ramos Burkitt's lymphoma B...

In the treatment of autoimmune diseases, intravenous Igs (IVIg) are assumed to modulate immune cells through the binding of surface receptors. IVIg act upon definite human B cell populations to modulate Ig repertoire, and such modulation might proceed through intracellular signaling. However, the heterogeneity of human B cell populations complicates investigations of the intracellular pathways ...

normal 0 false false false en-us x-none ar-sa background: more than 100,000 iranian veterans and civilians still suffer from various long-term complications due to their exposure to sulfur mustard (sm) during the iran–iraq war in 1983–88. the aim of the study was to investigate dna damage of sm in veterans who were exposed to sm, 23–27 years prior to this study. materials and methods: blood sam...

objective(s):  chlorpyrifos (cp) is a broad-spectrum organophosphorus pesticide used extensively in agricultural and domestic pest control, accounting for 50% of the global insecticidal use. in the present study, protective effects of two selenium-enriched strong antioxidative medicines imod and angipars were examined in human lymphocytes treated with cp in vitro. materials and methods: isolate...