Lipoid proteinosis (LP) is an extremely rare autosomal recessive genodermatosis, characterized by persistent hoarseness and classical skin lesions. Amorphous hyaline depositions may affect any organ, but mainly the face extremities. These cause limitations in tongue movement, hence, difficulty speaking. Biopsies of lesions usually show massive deposits homogeneous, acidic, hyaline-like material...

Mallory's (;alcoholic') hyaline has been found in hepatocytes in 18 of 70 patients with primary biliary cirrhosis. These inclusions have previously been noted in only three cases of primary biliary cirrhosis. Current views on the nature of Mallory's hyaline are briefly discussed.

Infantile systemic hyalinosis is a rare disorder characterized by widespread deposition of hyaline. They usually present with skin lesions, joint contractures, and intractable diarrhea. We report a 2 year 4 month old boy with growth retardation, typical facial appearance, gingival enlargement, generalized stiff skin, joint contractures, and intermittent diarrhea. Skin biopsy revealed depositio...

AIMS We retrospectively analyzed clinicopathologic features of 8 cases of hepatitis B virus-associated glomerulonephritis with hyaline thrombi, to confirm the diagnosis of cryoglobulinemic glomerulonephritis (CRYGN) associated with HBV infection. METHODS Retrospective analysis was carried out with demographic information, clinical manifestations, laboratory parameters, pathological and progno...

BACKGROUND Little is known about the relationship between splenic arteriolar hyaline and cause of death. The purpose of this retrospective study was to evaluate the clinicopathological significance of splenic arteriolar hyaline in autopsy cases and estimate the applicability of hyaline for diagnosing the cause and rapidity of death. METHODS Archival data and histological slides from 82 cases ...

INTRODUCTION It is common for leiomyoma to undergo various secondary changes like hyaline degeneration, cystic change, myxoid degeneration, infection, necrosis, calcification, red degeneration and very rarely ossification. They are said to result from inadequate blood supply resulting in replacement of muscle fibres by hyaline material, collagen, calcium, mucopolysaccharides or a combination of...

Renal hyaline droplet formation is described in two patients with haemoglobinuria. The droplets were shown to contain haemoglobin by a histochemical method. The findings are correlated with the results of recent experimental studies which have demonstrated that renal hyaline droplets are phagosomes containing absorbed protein and not products of cellular degeneration as was previously thought.

Light and scanning electron microscopic (SEM) examinations were used to study the hyaline zone and associated root resorption after orthodontic treatment of the upper first molars of rats. The orthodontic treatment consisted of a fixed buccal expansion appliance with an initial force of 250 mN. The animals were divided into nine experimental groups with orthodontic treatment and one control gro...

In former investigations (1) we observed the deposition of a hyaline substance in the connective tissue of the uterine mucosa and muscularis of mice injected with large doses of estrogen for a period of two months or longer. This hyaline material acted in certain respects like a foreign body, in some instances causing the formation of epithelioid and small giant cells which helped in its absorp...

The pathogenesis of hyaline membrane disease is not only unsolved but also highly controversial and 'there exist almost as many theories about it as there have been serious observers' (Stowens, 1959). Among these theories some are based on the assumption that circulatory disturbances play a role in the development of the hyaline membranes. Transudation of constituents of blood plasma has been c...