t rue saccular aneurysm is exceptional in coarctation of aorta in children. a 6-year-old girl with headache and systemic arterial hypertension referred to our center for cardiovascular evaluation. physical examination revealed high blood pressure and weak lower extremity pulses. two-dimensional and doppler echocardiography and angiography demonstrated a saccular aneurysm of the descending aorta...

Henoch-Schönlein purpura (HSP) is a systemic vasculitis involving small vessels with deposition of immunoglobulin A (IgA) complexes, usually affecting children. Compared with children, HSP in adults is more severe and frequently associated with cancer. We report the case of a 49-year-old woman with medical history of kidney transplantation for segmental glomerular hyalinosis. Eight years after ...

Key words: biopsy; combined heart and kidney trans-which clinical decisions can be based. That this may not always be the case is illustrated by the following. plantation; interstitial fibrosis A 59-year-old male patient with a history of long standing diabetes mellitus type II and coronary heart It is usually assumed that one renal biopsy, i.e. a random sample of 10–20 out of the approximately...

The histopathological changes in 51 renal allograft biopsies from patients immunosuppressed with FK506 were compared with those seen in 30 needle biopsies obtained from patients on cyclosporine. The frequency and severity of rejection episodes were similar in both groups. Tubular vacuolation and myocyte vacuolation were found to be useful morphological markers to monitor short-term drug toxicit...

BACKGROUND The classical description of FSGS includes segmental increase of mesangial matrix with obliteration of the capillaries, sclerosis, hyalinosis, foam cells, and segmental scarring, and adhesion between the glomerular tuft and Bowman’s capsule. A recently proposed pathology classification has pointed to the existence of nonsclerotic forms of FSGS. There has been a marked increase in the...

CASE SUMMARY An 8-year-old domestic shorthair neutered male cat was presented with acute onset of paraplegia, absent nociception on the pelvic limbs, tail and perianal area, and a previous history of uncontrolled hyperthyroidism (even after thyroidectomy) and chronic hypertension. The magnetic resonance findings (heterogeneous intramedullary ill-defined area, isointense on T1-weighted and hyper...

BACKGROUND There is evidence that biopsy of stable renal allografts may be of value in predicting chronic allograft nephropathy, the main cause of graft loss. However, the reproducibility of such histological evaluation has not been tested in this setting. We tested the reproducibility of the Banff schema for this purpose. METHODS We rated acute and chronic changes in 184 protocol biopsies. I...

INTRODUCTION The primary nephrotic syndrome (PNS) is the most common glomerular nephropathy in children. Its diagnosis and management don't require histopathological study. It occurs mainly in the form of minimal glomerular lesion and in most cases respond to corticosteroids. The literature on histological lesions of pure PNS in adolescents and young adults is rare. Thus, there are no criteria ...

Differential resistance spectra (dV/dI-V characteristics) have been measured for point contacts between the heavy-fermion superconductor (HFS) CePt(3)Si and a normal metal. Some contacts show a peak at V = 0 that is characteristic of HFS coexisting with a magnetic order such as UPd(2)Al(3), UNi(2)Al(3) and URu(2)Si(2). The evolution of the peak occurs well above the antiferromagnetic transition...