We show that three different morphologies exist near the two-phase boundary of ternary systems containing a hydrotropic cosolvent. Based on synchrotron small- and wide-angle X-ray scattering combined with molecular dynamics, we rationalize the specific scattering signature of direct, bicontinuous, and reverse mesoscale solubilization. Surprisingly, these mesostructures are resilient toward stro...

The possibility to use glycerol carbonate (GlyC) as an innovative alkylating agent for phenolic compounds in solventless conditions and the presence of a catalytic amount both homogeneous heterogeneous bases is herein described. In particular, peculiar, polyfunctional structure GlyC allows one obtain formation not only mono-phenoxy-1,2-propanediol (MPP) analogue but also 1,3-diphenoxy-2-propano...

BACKGROUND Aggregation of unfolded proteins occurs mainly through the exposed hydrophobic surfaces. Any mechanism of inhibition of this aggregation should explain the prevention of these hydrophobic interactions. Though arginine is prevalently used as an aggregation suppressor, its mechanism of action is not clearly understood. We propose a mechanism based on the hydrophobic interactions of arg...