Three women with hypoparathyroidism are described who developed severe symptomatic hypercalcaemia while being treated with alphacalcidol (1 alpha-hydroxycholecalciferol; One-Alpha). One sustained permanent renal damage. Alphacalcidol may have advantages over calciferol in its speed of action but poisoning may be more likely to occur. Frequent follow-up checks on the plasma calcium is needed for...

In order to clarify how we collect saliva for analyzing salivary protein in aged subjects who can not eat well, we compared the effects of suction, spitting and the swab saliva collection method on the yield of protein components in saliva samples from normal volunteers. The saliva collected by suction, spitting and the swab method were designated as, Saliva I, II and III, respectively. The sal...

Current methods for forensic identification of saliva generally assay for the enzymatic activity of alpha-amylase, an enzyme long associated with human saliva. Here, we describe the Rapid Stain IDentification (RSID-Saliva), a lateral flow immunochromatographic strip test that uses two antisalivary amylase monoclonal antibodies to detect the presence of salivary amylase, rather than the activity...

Cigarette smoke is injurious to both oral cavity and internal body environment. Saliva is the firstbody fluid to encounter the dangerous smoke. The aim of our present study was, therefore, toevaluate the influence of smoking on the antioxidant activity of saliva of healthy smokers.Antioxidant capacity of saliva was determined using different methods in the centrifuged saliva from25 male smokers...

Previous studies have shown that saliva is an important specimen for the diagnosis of congenital Cytomegalovirus (CMV). It is not only easy to collect without trauma to the newborn but neonates shed large volume of the virus in their saliva. Saliva which usually carry high viral load in infected patients especially in children, contain several components which inhibit the sensitivity of Polymer...

Background: Saliva is an alternative biological matrix in drug testing. It has several advantages in comparison with other biological fluids such as blood and urine. Collection of saliva is simple, noninvasive and can be controlled under direct observation in drug abusers, or opium addicts. Methods: In the present study we report our experience with saliva collection, liquid-liquid extraction a...