نتایج جستجو برای: hyperpigmented patch
تعداد نتایج: 42367 فیلتر نتایج به سال:
A 75-year-old woman with a history of hydroxychloroquinetreated cutaneous lupus erythematosus presented with a bilateral sharply demarcated macular hyperpigmentation on both forearms (Fig. 1) and a partial melanonychia of the right thumb nail. This pigmentation disorder developed gradually over a 6-month period. No retinal pigmentation and no systemic disorder were revealed. Dermoscopy of the n...
BACKGROUND Skin pigmentary changes of pityriasis versicolor may occur as either hyperpigmented or hypopigmented lesions, depending on the outcome of interactions between Malassezia yeasts and the skin, such as lipoperoxidation process, stimulus of inflammatory cell to melanocytes, and increased thickness of keratin layer. OBJECTIVE To investigate skin characteristic factors that enhance the s...
Rationale: cAMP up-regulates microphthalmia-associated transcription factor subtype M (MITF-M) and tyrosinase (Tyro) in the generation of heavily pigmented melanosomes. Here, we communicate a therapeutic mechanism of hyperpigmented disorder by α-viniferin, an active constituent of Caragana sinica. Methods: We used cAMP-elevated melanocyte cultures or facial hyperpigmented patches for pigmentati...
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