The hypolipidemic effect of an exo-biopolymer produced from a submerged mycelial culture of Hericium erinaceus was investigated in dietary-induced hyperlipidemic rats. Hypolipidemic effects were proportionally increased with the increasing concentration of the exo-biopolymer for oral administration. The exo-biopolymer, at the dose of 200 mg/kg body weight, substantially reduced the plasma total...

The present study investigates the hypolipidemic effect of aqueous extract of whole plant of Melothria maderaspatana (AEMM) in high fat diet fed rats. In this study three doses (0.5, 1 and 2 gm kg) of AEMM were used. Treatment with AEMM (2 gm kg, p.o.) had shown significant reduction in the lipid level in high fat diet fed animals. The AEMM exhibited significantly hypolipidemic activity compara...

Isoflavones have been suggested to have hypolipidemic effects. As these compounds undergo complex metabolism in the body, the biological actions of isoflavone metabolites are largely unknown. We studied the hypolipidemic effects of two isoflavone metabolites initially identified in the human urine, cis-tetrahydrodaidzein (NV-04) and transtetrahydrodaidzein (NV-05) in apolipoprotein(E)-deficient...

Hyperlipidemia and many other metabolic diseases are related to oxidative stress. Centella asiatica is a traditional Chinese medicine whose antioxidant effect in vitro has been reported. We are interested in whether it possesses this effect in vivo and hence modulates lipid metabolism. Therefore, experiments were carried out on mice and golden hamsters regarding its antioxidant and hypolipidemi...

Dyslipidemia is one of the main risk factors for development cardiovascular diseases (CVD), which remain leading cause death worldwide. Lipid level control most effective strategy prevention CVD and its complications (CVC). Statins are first-line drugs hypolipidemic therapy. often found in patients with chronic liver (CLD). From a clinical point view, number CLD have an increased CVD. Due to in...

In this article it will be discussed actual issues and modern problems of the ischemic disease heart, antiplatelet therapy, its effects, hypolipidemic indications, counter potential side effects as well as, successful management strategies after percutaneous coronary intervention following with drug eluted stents.