Background: To investigate the incidence of anxiety and depressive disorders in young adults with obesity correlation between severity these hypothalamic inflammation.

Hypothalamic hamartoma is a potentially complex entity with diverse clinical manifestations. We report a case of gelastic seizures associated with a hypothalamic hamartoma, which followed a benign course. A 31-year-old woman with episodes of laughter was referred for diagnostic evaluation. Her initial MRI and EEG were reported as normal. However, her episodes of laughter were typical of gelasti...

COVIAN, MIGUEL R., AND Jo& ANTUNES-RODRIGUES. SpeciJic alterations in sodium chloride intake after hypothalamic lesions in the rat. Am. J. Physiol. 205(5): 922-926. 1963. -Bilateral electrolytic lesions in the hypothalamus of the rat elicited either a decrease or increase in 2 ‘;/;/ NaCl intake, without a significant change in water ingestion. Lesions placed in the anterior hypothalamus involvi...

Aging is characterized by autophagy impairment that contributes to age-related disease aggravation. Moreover, it was described that the hypothalamus is a critical brain area for whole-body aging development and has impact on lifespan. Neuropeptide Y (NPY) is one of the major neuropeptides present in the hypothalamus, and it has been shown that, in aged animals, the hypothalamic NPY levels decre...

background: stimulants addition and abuse can cause some functional and morphological changes in the normal function of glands and hormones. methamphetamine as an addictive stimulant drug affects the hypothalamic-pituitary-adrenal (hpa) axis and consequently makes some changes in the psychological state of the drug users. the present study aims to examine the relationship between plasma levels ...

We examined an obese 58-year-old patient with a bilateral posterior hypothalamic lesion of unknown etiology. A 24-hour polysomnography revealed a markedly increased total sleep time (17.6 h). During daytime, only 3 continuous wake phases occurred. REM periods occurred only between 5 p.m. and 6 a.m. We conclude from our results that, similar to the results from animal experiments, the posterior ...

introduction rapid-onset obesity with hypoventilation, hypothalamic dysfunction, and autonomic dysregulation (rohhad) is a rare disease. to date, there have been only few reported cases of rohhad syndrome. conclusions only a few case reports have described rohhad syndrome, and it is therefore difficult to manage. in children with rapid and early-onset obesity associated with hypothalamic-pituit...

IntroductionObesity is a multifactorial disease and defined by the excessive accumulation of adipose tissue that can cause harm to human health. The presence obesity an important risk factor for migraine chronification. However, not much known about link between two diseases. MethodsIn this study, integrative literature review was conducted better understand mechanisms interaction obesity. Ther...

BACKGROUND Blunted facial affect is a common negative symptom of schizophrenia. Additionally, assessing the trustworthiness of faces is a social cognitive ability that is impaired in schizophrenia. Currently available pharmacological agents are ineffective at improving either of these symptoms, despite their clinical significance. The hypothalamic neuropeptide oxytocin has multiple prosocial ef...

The role of the ventromedial nuclei of the hypothalamus (VMN) in food behavior was studied in adult male rats, allocated in 3 groups: control, sham and lesioned. Electrolytic lesions were induced stereotaxically (1.2 mA, 15 sec). Results revealed a significant decrease (p<O.05) in body weight (BW) and food intake (FI) in the order of lesioned <sham <control during the fIrst week. However, ...