Correspondence: Jean-Jacques Body, M.D., Ph.D., Institut Jules Bordet, Université Libre de Bruxelles, 1 Rue Héger-Bordet, 1000 Brussels, Belgium. Telephone: 32-2-541-3303; Fax: 32-2-541-3311; e-mail: [email protected] Received August 1, 2005; accepted for publication August 29, 2005. ©AlphaMed Press 1083-7159/2005/$12.00/0 Bisphosphonates are routinely used for managing metastatic bone disease....

During the 1020s Ibn Sı̄nā wrote a commentary in Arabic on the logical works of Aristotle, as part of his encyclopedia Al-Šifā’ (The Cure). The commentary runs to some 2180 pages in the recent Cairo edition; this figure includes his commentary Madk ̄ al on Porphyry’s Eisagōgē, which he counted as an introduction to Aristotle’s work. Apart from the Madk ̄ al which was translated into Latin in the 1...

Ibn Sina is regarded as one of the greatest physicians, thinkers and medical scholars in the history of medicine. Ibn Sina, a Persian scholar in the medieval era, wrote a famous book of medicine, the Canon of Medicine. The book was adopted as the main textbook of medicine in most Western and Persian universities. In the present critique, we analyzed the functional and anatomic descriptions of t...

This paper proposes a declarative language for knowledge representation (Ibn Rochd), and its environment of exploitation (DeGSE). This DeGSE system was designed and developed to facilitate Ibn Rochd writing applications. The system was tested on several knowledge bases by ascending complexity, culminating in a system for recognition of a plant or a tree, and advisors to purchase a car, for peda...

Osteoporosis is a chronic condition that generally requires long-term therapy for fracture risk reduction to become apparent. Although the bisphosphonates have made a major contribution to how clinicians manage osteoporosis, compliance with therapy has generally been less in the real-world setting than seen in clinical trials. Less-frequently administered dosage regimens or nonoral routes may e...

Karima Issara, Zouhour Boughaleb, Nezha Tawfiq, Zineb Bouchbika, Nadia Benchakroun, Hassan Jouhadi, Souha Sahraoui, Abdellatif Benider Centre Mohammed VI de Traitement des Cancers, CHU Ibn Rochd, Faculté de Médecine et Pharmacie, Université Hassan II, Casablanca, Maroc Corresponding author: Karima Issara, Centre Mohammed VI de Traitement des Cancers, CHU Ibn Rochd, Faculté de Médecine et Pharma...

BACKGROUND Osteoporosis is a frequent complication in patients with inflammatory bowel disease. Recent studies have shown bisphosphonates to considerably reduce fracture risk in patients with osteoporosis, and preventing fractures with bisphosphonates has been reported to be cost effective in older populations. However, no studies of the cost effectiveness of these agents in preventing fracture...

UNLABELLED Fat hypertrophy, intravascular coagulation, and fat emboli are important risk factors of steroid-induced ischemic bone necrosis (SI-IBN) which may develop during the initial one year after commencing the use of steroids. This pathology is best studied by MRI, particularly for its staging. The cautious strategies such as low dose, oral route, short duration of steroid usage, use of st...

To develop a carrier for use in enzyme prodrug therapy, Horseradish peroxidase (HRP) was immobilized onto mesoporous silica nanoparticles (IBN-4: Institute of Bioengineering and Nanotechnology), where the nanoparticle surfaces were functionalized with 3-aminopropyltrimethoxysilane and further conjugated with glutaraldehyde. Consequently, the enzymes could be stabilized in nanochannels through t...