To study the structural and functional roles of the cysteine residues at positions 36, 41, and 46 in the transmembrane domain of phospholamban (PLB), we have used Fmoc (N-(9-fluorenyl)methoxycarbonyl) solid-phase peptide synthesis to prepare alpha-amino-n-butyric acid (Abu)-PLB, the analogue in which all three cysteine residues are replaced by Abu. Whereas previous studies have shown that repla...

During asymptomatic bacteriuria (ABU), bacteria colonize the urinary tract for extended periods of time without causing symptoms of urinary tract infection. Previous studies indicate that many Escherichia coli (E. coli) strains that cause ABU have evolved from uropathogenic E. coli (UPEC) by reductive evolution and loss of the ability to express functional virulence factors. For instance, the p...

PURPOSE This study evaluated the influence of bone marrow cell collection techniques and donor site locations on the in-vitro growth of bone-forming cells. METHODS Sixty six samples of bone marrow cell collections (BMCC) or bone marrow aspirates (BMA) from 15 patients were obtained. Thirty eight samples for culture were composed of 23 BMA from 7 tibial condyles and 16 ilia, with the other 15 ...

Fung 11, Abu-Elmagd K, Todo S, Shapiro R, Tzakis A, Jordan M, Armitage J, Jain A, Martin M, Bronster 0, Stieber A, Kormos R, Selby R, Gordon R, Starzl TE. FK506 in clinical organ transplantation. John J. Fung, Kareem Abu-Elmagd, Saloro Todo, Ronald Shapiro, Andreas Tzakis, Mark Jordan, John Armitage, Ashok Jain, Maureen Martin, Oscar Bronster, Andrei Stieber, Robert Kormos, Robert Selby, Robert...

Studies show that the pH of the malaria parasite’s digestive vacuole (DV) plays a key role in the physiological functions of this organelle and antimalarial drug accumulation, and yet is technically difficult to measure. In this study, a flow cytometry-based technique was developed to measure the DV pH using a ratiometric pH indicator, FITC-dextran loaded into the DV of saponin-permeabilized pa...

Una entrevista con Narel Paniagua-Zambrana, investigadora principal del Departamento de Etnobotánica Instituto Botánica la Universidad Estatal Ilia, Georgia, asociado Herbario Nacional Bolivia y co-directora Saving Knowledge. Su trabajo se centra en investigación etnobotánica preservación conocimiento tradicional los Andes, el Cáucaso Himalaya.

The aim of this purpose was to compare injury mechanism in boys’ amateur epical athletes in Kyokushin, Karate and Aikido. 95 Aikido athletes, 83 Kyokushin ka athletes, 76 Karate ka were randomly selected from Shiraz clubs. Data were analyzed by Χ test. The results showed that the rate of injuries in Kyokoshin was (24.1%), Karate (19.5%) (X=448.46, P=0.000). In all three fields, there were injur...

As a country, the United Arab Emirates has developed very rapidly from a developing country with a largely nomadic population, to a modern and wealthy country with a Western lifestyle. This economic progress has brought undoubted social benefits and opportunities for UAE citizens, including a high and increasing life expectancy. However, rapid modernization and urbanization have contributed to ...

BACKGROUND Catheter-associated urinary tract infection (CAUTI) is one of the most common hospital-acquired infections. However, many cases treated as hospital-acquired CAUTI are actually asymptomatic bacteriuria (ABU). Evidence-based guidelines recommend that providers neither screen for nor treat ABU in most catheterized patients, but there is a significant gap between these guidelines and cli...

INTRODUCTION Urinary tract infection (UTI) occurs in 1.1% of girls and 1.4% of boys during the first year of life. Asymptomatic bacteriuria (ABU) is usually detected incidentally in 0.9% of girls and 2.5% of boys at this age. The aim of the study was to assess the usefulness of measurement of pro-inflammatory urine interleukin (IL)-6 and IL-8 concentrations and anti-inflammatory transforming gr...