After pacemaker/implantable cardioverter-defibrillator (pacemaker/ICD) implantation, patients are often required to immobilize the affected arm with a sling to minimize the risk of lead displacement. We examined whether performing a resistive range-of-motion exercise protocol after pacemaker/ICD surgery would result in lead displacement and, therefore, whether sling immobilization and activity ...

Planarians are an important model organism for regeneration and stem cell research. A complete understanding of stem cell and regeneration dynamics in these animals requires time-lapse imaging in vivo, which has been difficult to achieve due to a lack of tissue-specific markers and the strong negative phototaxis of planarians. We have developed the Planarian Immobilization Chip (PIC) for rapid,...

Silicon nanowire (Si NW)-based field effect transistors (FETs) have shown great potential as biosensors (bioFETs) for ultra-sensitive and label-free detection of biomolecular interactions. Their sensitivity depends not only on the device properties, but also on the function of the biological recognition motif attached to the Si NWs. In this study, we show that SiNWs can be chemically functional...

A noninvasive localization and immobilization technique that facilitates planning and accurate delivery of both intensity modulated radiotherapy (IMRT) and linac based stereotactic radiotherapy (SRT) of intracranial tumors has been developed and clinically tested. Immobilization of a patient was based on a commercially available Gill-Thomas-Cossman (GTC) relocatable frame. A stereotactic locali...

Bacteria have evolved complex, highly-coordinated, multi-component cellular engines to achieve high degrees of efficiency, accuracy, adaptability, and redundancy. Super-resolution fluorescence microscopy methods are ideally suited to investigate the internal composition, architecture, and dynamics of molecular machines and large cellular complexes. These techniques require the long-term stabili...

Development of a simple and efficient methodology to control the placement, spacing, and alignment of single-walled carbon nanotubes (SWCNTs) is essential for nanotechnology device application. Building on the growing understanding that the strong π-π interaction between the bases of single-stranded DNA (ssDNA) and CNTs is sufficient not only to drive CNT solubility in water but also to stabili...