Immune privilege is used by the eye, brain, reproductive organs, and gut to preserve structural and functional integrity in the face of inflammation. The eye is arguably the most vulnerable and, therefore, also the most "privileged" of tissues; paradoxically, it remains subject to destructive autoimmunity. It has been proposed, although never proven in vivo, that the eye can induce T regulatory...

Immune privilege was originally believed to be associated with particular organs, such as the testes, brain, the anterior chamber of the eye, and the placenta, which need to be protected from any excessive inflammatory activity. It is now becoming clear, however, that immune privilege can be acquired locally in many different tissues in response to inflammation, but particularly due to the acti...

Article history: Received on: 14/12/2014 Revised on: 08/01/2015 Accepted on: 22/01/2015 Available online: 27/02/2015 Testis is the tissue with immune privilege which is maintained by blood-testis barrier to protect autoimmunogenic components of testis. IgG have binding affinity for CD16, CD32 and CD64 receptors present on various immune cells. Present study was conducted to investigate the IgG ...

Sparse Raman-based models can reach high accuracy and stability for the prediction of fine biological processes (immune activation protein synthesis), privilege use side bands discriminating cellular differences.

Tumour and myeloid cell interactions that occur in the brain are exposed to unique microenvironmental conditions. While tumour outgrowth ultimately has a major impact, the intrinsic properties of the brain initially impose the framework on which subsequent cellular interactions must build. The particularities of the brain are partly anatomical, with strictly controlled traffic of cells and mole...

The immune system is a highly parallel and distributed intelligent system which has learning, memory, and associative capabilities. Artificial Immune System is an evolutionary paradigm inspired by the biological aspects of the immune system of mammals. The immune system can inspire to form new algorithms learning from its course of action. The human immune system has motivated scientists and en...

The adaptive immune system of placental mammals has evolved to tolerate the fetus. Rejection of the fetus by adaptive immune responses is therefore a rare event, with abortion being caused more frequently by inflammation in the placenta. This review will cover recent aspects of immune privilege and the innate immune system at the feto-maternal interface, citing examples of the role played by mi...

Although long granted the status of immune privilege, the central nervous system is not completely isolated from the immune system. Increasing evidence suggests that this system contributes to seizures and epilepsy and that the molecular mediators of inflammation and immunity may serve as appropriate targets in the quest to develop novel antiepileptic drugs that are more efficacious and potenti...