Significant progress has been made in methods for cardiac repair and regeneration within the past few decades; however, diseased microenvironment of infarct remains a limitation efficacy therapies. A breadth research is currently aiming to reverse this environment, focusing on immunomodulation, scavenging oxidative species, increasing oxygen levels tissue, either directly using materials or the...

The complexity of multiple sclerosis (MS) and the incompetence of a large number of promise treatments in MS urge us to plan new and more effective therapeutic approaches that aim to suppress ongoing autoimmune responses and induction of local endogenous regeneration. Emerging data propose that hematopoietic, mesenchymal and neural stem cells have the potential to restore self-tolerance, to pro...

A dysregulated immune response characterized by the hyperproduction of several pro-inflammatory cytokines (a.k.a. ‘cytokine storm’) plays a central role in pathophysiology severe coronavirus disease 2019 (COVID-19) caused acute respiratory syndrome 2 (SARS-CoV-2). In this Perspective article we discuss evidence for synergistic anti-inflammatory and immunomodulatory properties exerted vitamin D ...

1 Department of Psychoimmunology, National Institute of Psychiatry “Ramón de la Fuente”, Calzada México-Xochimilco 101, Colonia San Lorenzo Huipulco, Tlalpan, 14370 Mexico City, DF, Mexico 2 Research Group Immunophysiology, Institute of Physiology and Pathophysiology, Philipps University, 35037 Marburg, Germany 3 Instituto de Inmunologı́a, Facultad de CienciasMédicas, UniversidadNacional de Rosa...