نتایج جستجو برای: immunomodulators
تعداد نتایج: 1590 فیلتر نتایج به سال:
Polysaccharide immunomodulators were first discovered over 40 years ago. Although very few have been rigorously studied, recent reports have revealed the mechanism of action and structure-function attributes of some of these molecules. Certain polysaccharide immunomodulators have been identified that have profound effects in the regulation of immune responses during the progression of infectiou...
BACKGROUND Since the treatment guidelines for atopic dermatitis (AD) were issued by the Korean Atopic Dermatitis Association (KADA) work group in 2006, there have been further advances in the systemic treatment of AD. OBJECTIVE We aimed to establish updated evidence- and experience-based systemic treatment guidelines for Korean AD. METHODS We compiled a database of references from relevant ...
Ticks are significant bloodsucking ectoparasites. Apart from causing blood loss and host skin damage, ticks are important vectors of tick-borne pathogens that cause disease in humans and animals as well as significant economic loss. For biological success, ticks evolved these substances with immunomodulatory activities capable of inhibiting host defence reactions (haemostasis, inflammation and ...
Azathioprine, 6-MP and Methotrexate were developed for cancer chemotherapy, but when used in small doses, they can be helpful for treating chronic inflammatory diseases such as IBD and some forms of arthritis. These are medications that reduce (suppress) the activity of the immune system by suppressing the bone marrow where immune cells are formed. These medications are called immunosuppressive...
Medicinal plants play significant roles in the prevention of human beings from various pathogenic microorganisms and diseases. The immunomodulators are agents used to modulate immune system can be obtained both natural as well synthetic origin chemicals. Alteration within is often achieved by immunomodulatory a plant source, low molecular weight compounds like alkaloids other nitrogen-containin...
OBJECTIVE To review the literature on the role of autoimmunity in the etiology of endometriosis, compare the similarities in the pathophysiologies between endometriosis and autoimmune diseases, and discuss the use of immunomodulators currently used to treat autoimmune diseases as potential therapies for endometriosis. DESIGN The literature on endometriosis and other autoimmune diseases was re...
We have previously shown that prophylactic administration of the liposome-encapsulated immunomodulating agents muramyl tripeptide phosphatidylethanolamine (MTPPE) and gamma interferon (IFN-gamma) results in strongly increased survival of mice from a normally lethal septicemia with Klebsiella pneumoniae. It was anticipated that the treatment acts on macrophages and nonspecifically augments host ...
Multiple sclerosis (MS) is a chronic autoimmune disease that usually affects young adults, causing progressive physical and cognitive disability. Since the 1990s, its treatment has been based on parenteral medications known collectively as immunomodulators. This drug class is considered safe and usually prevents 30% of MS relapses. Drugs in this class exert almost the same efficacy and require ...
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