Antibiotics (antibacterial, antiviral, and antiparasitic) are class of drugs which result in either killing or inhibiting growth and multiplication of infectious organisms. Antibiotics are commonly prescribed by all specialties for treatment of infections. However, antibiotics have hitherto immunomodulatory and anti-inflammatory properties and can be exploited for various noninfectious dermatos...

Infliximab is a chimeric anti-tumour necrosis factor-alpha antibody that is efficacious in treating Crohn's disease. However, its immunomodulatory properties increase susceptibility to opportunistic infections. We present a case of cutaneous Nocardia infection in a patient who was taking infliximab for Crohn's disease. The case illustrates the challenges in the diagnosis and management of this ...

Modulation of immune response to alleviate diseases has long since been of interest. Recent progress on the ethnomedicinal plants as immunomodulatory agent reported from 2000 to early 2008 is reviewed. Plant extracts have been widely investigated in this time in different parts of the world for their possible immunomodulatory properties. Some of the studies demonstrated to the isolation of pote...

The human gingiva, characterized by its outstanding scarless wound healing properties, is a unique tissue and a pivotal component of the periodontal apparatus, investing and surrounding the teeth in their sockets in the alveolar bone. In the last years gingival mesenchymal stem/progenitor cells (G-MSCs), with promising regenerative and immunomodulatory properties, have been isolated and charact...

Immunomodulation is a procedure, which can alter the immune system of an organism by interfering its function. Modulation of immune system may result in suppression or stimulation of immunological reactivity. Recently the effect of immunomodulators in the treatment of various diseases is significant. Tinosporacordifolia is a widely used shrub in ayurvedic system of medicine. It is reported ...

immunomodulation is a procedure, which can alter the immune system of an organism by interfering its function. modulation of immune system may result in suppression or stimulation of immunological reactivity. recently the effect of immunomodulators in the treatment of various diseases is significant. tinosporacordifolia is a widely used shrub in ayurvedic system of medicine. it is reported to b...

Mesenchymal Stromal/Stem (MSCs) cells possess a remarkable capacity as therapeutic option for many diseases. These have immunomodulatory, proangiogenic, regenerative and anti-inflammatory capabilities. In spite of possessing such properties, these behave differently in the in-vivo environment diseased condition, instances lose their potential. This case report presents evidence about empowermen...

BACKGROUND Mesenchymal stromal cells (MSCs) possess potent immunomodulatory properties that increase their value as a cell-based therapeutic tool for managing various immune-based disorders. Over the past years, accumulated results from trials using MSCs-based therapy have shown substantial contradictions. Although the reasons underlying these discrepancies are still not completely understood, ...

For the application of mesenchymal stem cells (MSCs) as clinical therapeutics, the regulation of cellular aging is important to protect hMSCs from an age-associated decline in their function. In this study, we evaluated the effects of hypoxia on cellular senescence and the immunomodulatory abilities of hUCB-MSCs. Hypoxic-cultured hUCB-MSCs showed enhanced proliferation and had increased immunos...