Dermatological complications of long-term immunosuppressive therapy in inflammatory bowel disease (IBD) are rarely reported. We present the case of a 29-year-old man with worsening of plantar warts while on azathioprine therapy for Crohn's disease. This case underlines the need to perform thorough skin examination of IBD patients before and during immunosuppressive therapy.

OBJECTIVE To study the frequency of HLA DR2 status of patients with aplastic anemia and their response to immunosuppressive therapy at a tertiary care hospital. METHODS Thirty eight consecutive patients of acquired aplastic anemia were evaluated with respect to demographic features, severity of HLA DR2 status and response outcome to immunosuppressive therapy. RESULTS The mean age of the pat...

Patients with systemic lupus erythematosus (SLE) who present with skin disease pose the clinician with diagnostic challenges. The skin disease can reflect an increase in systemic disease activity suggested by other features of active lupus and, as such, usually responds well to more aggressive immunosuppressive therapy. Other possibilities of skin disease include drug eruptions, skin disease un...

OBJECTIVE After an initially successful islet cell transplantation, a number of patients return to C-peptide negativity, and therefore immunosuppressive therapy is discontinued. Some are then found to have developed Graves disease. We examined the risk of Graves disease after immunosuppression. RESEARCH DESIGN AND METHODS Immunosuppressive therapy was stopped in 13 type 1 diabetic islet cell ...

PURPOSE Limited data are available on immunologic responses to primary pandemic H1N1 (2009) vaccination in recipients of allogeneic hematopoietic stem cell transplantation (HSCT) recipients. In 2009 serologic responses to either pandemic H1N1 (2009) vaccine (n = 36) or pandemic H1N1 (2009) infection (n = 2) were studied in 38 HSCT recipients. METHODS Responses were measured with a standard he...

Idiopathic membranous nephropathy (iMN) is one of the most common causes of the nephrotic syndrome in adults. The clinical course of patients with iMN is quite variable. Untreated, ∼40–50% of patients with iMN and nephrotic proteinuria will develop end-stage renal disease (ESRD) [1]. According to data of registries in the USA, Europe, and Australia and New Zealand, MN was the cause of ESRD in 0...